Identity
HGNC
LOCATION
6q22.33
LOCUSID
ALIAS
CRISTIN1,PWTSR,THSD2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84870
MIM: 610574
HGNC: 20866
Ensembl: ENSG00000146374
Variants:
dbSNP: 84870
ClinVar: 84870
TCGA: ENSG00000146374
COSMIC: RSPO3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000146374 | ENST00000356698 | Q9BXY4 |
| ENSG00000146374 | ENST00000368317 | Q9BXY4 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37173190 | 2023 | Amniotic fluid stem cell attenuated necrotizing enterocolitis progression by promoting Rspo3/AMPKα axis. | 1 |
| 37932819 | 2023 | Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma. | 0 |
| 37173190 | 2023 | Amniotic fluid stem cell attenuated necrotizing enterocolitis progression by promoting Rspo3/AMPKα axis. | 1 |
| 37932819 | 2023 | Upregulation of RSPO3 via targeted promoter DNA demethylation inhibits the progression of cholangiocarcinoma. | 0 |
| 35995979 | 2022 | RSPO3 is a novel contraction-inducible factor identified in an "in vitro exercise model" using primary human myotubes. | 2 |
| 36129915 | 2022 | Investigation of cell signalings and therapeutic targets in PTPRK-RSPO3 fusion-positive colorectal cancer. | 0 |
| 35995979 | 2022 | RSPO3 is a novel contraction-inducible factor identified in an "in vitro exercise model" using primary human myotubes. | 2 |
| 36129915 | 2022 | Investigation of cell signalings and therapeutic targets in PTPRK-RSPO3 fusion-positive colorectal cancer. | 0 |
| 33320737 | 2021 | R-Spondins 2 and 3 Are Overexpressed in a Subset of Human Colon and Breast Cancers. | 6 |
| 34389713 | 2021 | RSPO3 is important for trabecular bone and fracture risk in mice and humans. | 16 |
| 33320737 | 2021 | R-Spondins 2 and 3 Are Overexpressed in a Subset of Human Colon and Breast Cancers. | 6 |
| 34389713 | 2021 | RSPO3 is important for trabecular bone and fracture risk in mice and humans. | 16 |
| 31851527 | 2020 | R-spondin3 promotes the tumor growth of choriocarcinoma JEG-3 cells. | 7 |
| 31990902 | 2020 | Elevated levels of the secreted wingless agonist R-spondin 3 in preeclamptic pregnancies. | 1 |
| 32160239 | 2020 | Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. | 16 |
Citation
Dessen P
RSPO3 (R-spondin 3)
Atlas Genet Cytogenet Oncol Haematol. 2012-10-01
Online version: http://atlasgeneticsoncology.org/gene/52917/rspo3
