CENPK (centromere protein K)

2012-11-01  

Identity

HGNC
CENPK
LOCATION
5q12.3
LOCUSID
64105
ALIAS
AF5alpha,CENP-K,FKSG14,P33,Solt
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 64105
MIM: 611502
HGNC: 29479
Ensembl: ENSG00000123219

Variants:

dbSNP: 64105
ClinVar: 64105
TCGA: ENSG00000123219
COSMIC: CENPK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123219ENST00000242872Q9BS16
ENSG00000123219ENST00000396679Q9BS16
ENSG00000123219ENST00000502997D6RAX0
ENSG00000123219ENST00000505960D6R984
ENSG00000123219ENST00000508421D6RHD3
ENSG00000123219ENST00000509397H0Y9K8
ENSG00000123219ENST00000510354D6R984
ENSG00000123219ENST00000510693D6RJF0
ENSG00000123219ENST00000510768D6RBN6
ENSG00000123219ENST00000514814Q9BS16
ENSG00000123219ENST00000515497D6RC76

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Chromosome MaintenanceREACTOMER-HSA-73886
Nucleosome assemblyREACTOMER-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromereREACTOMER-HSA-606279

References

Pubmed IDYearTitleCitations
386702202024CENPK orchestrates ovarian cancer progression via GOLPH3-Mediated activation of mTOR signaling.0
386702202024CENPK orchestrates ovarian cancer progression via GOLPH3-Mediated activation of mTOR signaling.0
354181602022N(6)-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance.21
357156582022Centromeric protein K (CENPK) promotes gastric cancer proliferation and migration via interacting with XRCC5.1
363128392022Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A.0
354181602022N(6)-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance.21
357156582022Centromeric protein K (CENPK) promotes gastric cancer proliferation and migration via interacting with XRCC5.1
363128392022Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A.0
339043812021Overexpression of centromere protein K (CENPK) gene in Differentiated Thyroid Carcinoma promote cell Proliferation and Migration.5
339043812021Overexpression of centromere protein K (CENPK) gene in Differentiated Thyroid Carcinoma promote cell Proliferation and Migration.5
180459862008KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates.104
180459862008KNL1 and the CENP-H/I/K complex coordinately direct kinetochore assembly in vertebrates.104

Citation

Dessen P

CENPK (centromere protein K)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52980/js/css/gene-explorer/