Identity
HGNC
LOCATION
Xq28
LOCUSID
ALIAS
DC44,HCBP6,HCC3,PD03104
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 65991
MIM: 301042
HGNC: 24925
Ensembl: ENSG00000165775
Variants:
dbSNP: 65991
ClinVar: 65991
TCGA: ENSG00000165775
COSMIC: FUNDC2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165775 | ENST00000369498 | Q9BWH2 |
| ENSG00000165775 | ENST00000456179 | H7C0K8 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37700593 | 2023 | FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway. | 1 |
| 37700593 | 2023 | FUNDC2, a mitochondrial outer membrane protein, mediates triple-negative breast cancer progression via the AKT/GSK3β/GLI1 pathway. | 1 |
| 35468421 | 2022 | Methylation of the HCBP6 promoter is associated with primary biliary cholangitis pathogenesis. | 0 |
| 35710796 | 2022 | FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion. | 12 |
| 35468421 | 2022 | Methylation of the HCBP6 promoter is associated with primary biliary cholangitis pathogenesis. | 0 |
| 35710796 | 2022 | FUNDC2 promotes liver tumorigenesis by inhibiting MFN1-mediated mitochondrial fusion. | 12 |
| 29786068 | 2019 | Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway. | 21 |
| 29786068 | 2019 | Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway. | 21 |
| 29187281 | 2018 | HCBP6 upregulates human SREBP1c expression by binding to C/EBPβ-binding site in the SREBP1c promoter. | 1 |
| 29187281 | 2018 | HCBP6 upregulates human SREBP1c expression by binding to C/EBPβ-binding site in the SREBP1c promoter. | 1 |
| 25855506 | 2015 | HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway. | 7 |
| 25855506 | 2015 | HCBP6 Modulates Triglyceride Homeostasis in Hepatocytes Via the SREBP1c/FASN Pathway. | 7 |
Citation
Dessen P
FUNDC2 (FUN14 domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-11-01
Online version: http://atlasgeneticsoncology.org/gene/53002/fundc2
