SLC26A6 (solute carrier family 26 member 6)

2012-11-01  

Identity

HGNC
LOCATION
3p21.31
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 65010
MIM: 610068
HGNC: 14472
Ensembl: ENSG00000225697

Variants:

dbSNP: 65010
ClinVar: 65010
TCGA: ENSG00000225697
COSMIC: SLC26A6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000225697ENST00000307364F8W9I8
ENSG00000225697ENST00000337000G3XAC1
ENSG00000225697ENST00000358747A0A0C4DFT5
ENSG00000225697ENST00000383733Q9BXS9
ENSG00000225697ENST00000395550Q9BXS9
ENSG00000225697ENST00000414944H7BZB1
ENSG00000225697ENST00000420764Q9BXS9
ENSG00000225697ENST00000421649H7BZJ6
ENSG00000225697ENST00000426599C9J6Y3
ENSG00000225697ENST00000431213H7BZ36
ENSG00000225697ENST00000431739C9JKR6
ENSG00000225697ENST00000444531H7C291
ENSG00000225697ENST00000455886Q9BXS9

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Multifunctional anion exchangersREACTOMER-HSA-427601

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
343264802021Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.9
344589282021SLC26A6 and NADC‑1: Future direction of nephrolithiasis and calculus‑related hypertension research (Review).1
345913932021Up-Regulation of SLC26A6 in Hepatocellular Carcinoma and Its Diagnostic and Prognostic Significance.5
343264802021Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism.9
344589282021SLC26A6 and NADC‑1: Future direction of nephrolithiasis and calculus‑related hypertension research (Review).1
345913932021Up-Regulation of SLC26A6 in Hepatocellular Carcinoma and Its Diagnostic and Prognostic Significance.5
324329262020TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin.22
324329262020TNFα and IL-17 alkalinize airway surface liquid through CFTR and pendrin.22
307424932019Pendrin Mediates Bicarbonate Secretion and Enhances Cystic Fibrosis Transmembrane Conductance Regulator Function in Airway Surface Epithelia.30
310424222019miR-125a-5p: a novel regulator of SLC26A6 expression in intestinal epithelial cells.6
315391422019Novel SLC26A6 gene polymorphism rs184187143 is associated with diabetic ketoacidosis of gestational diabetes.2
307424932019Pendrin Mediates Bicarbonate Secretion and Enhances Cystic Fibrosis Transmembrane Conductance Regulator Function in Airway Surface Epithelia.30
310424222019miR-125a-5p: a novel regulator of SLC26A6 expression in intestinal epithelial cells.6
315391422019Novel SLC26A6 gene polymorphism rs184187143 is associated with diabetic ketoacidosis of gestational diabetes.2
300208252018Adenosinergic signaling inhibits oxalate transport by human intestinal Caco2-BBE cells through the A(2B) adenosine receptor.4

Citation

Dessen P

SLC26A6 (solute carrier family 26 member 6)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/53046/slc26a6