Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30846
MIM: 605890
HGNC: 3243
Ensembl: ENSG00000024422
Variants:
dbSNP: 30846
ClinVar: 30846
TCGA: ENSG00000024422
COSMIC: EHD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000024422 | ENST00000263277 | Q9NZN4 |
| ENSG00000024422 | ENST00000263277 | A0A024R0S6 |
| ENSG00000024422 | ENST00000538399 | Q9NZN4 |
| ENSG00000024422 | ENST00000596225 | M0R1B9 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Endocytosis | KEGG | ko04144 |
| Endocytosis | KEGG | hsa04144 |
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35177645 | 2022 | Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer. | 31 |
| 35412955 | 2022 | Circular RNA Eps15-homology domain-containing protein 2 induce resistance of renal cell carcinoma to sunitinib via microRNA-4731-5p/ABCF2 axis. | 3 |
| 35177645 | 2022 | Hypoxia-induced macropinocytosis represents a metabolic route for liver cancer. | 31 |
| 35412955 | 2022 | Circular RNA Eps15-homology domain-containing protein 2 induce resistance of renal cell carcinoma to sunitinib via microRNA-4731-5p/ABCF2 axis. | 3 |
| 33356637 | 2021 | EHD2 Overexpression Suppresses the Proliferation, Migration, and Invasion in Human Colon Cancer. | 3 |
| 33356637 | 2021 | EHD2 Overexpression Suppresses the Proliferation, Migration, and Invasion in Human Colon Cancer. | 3 |
| 32170013 | 2020 | EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. | 28 |
| 32945345 | 2020 | TUSC8 inhibits the development of osteosarcoma by sponging miR‑197‑3p and targeting EHD2. | 9 |
| 32170013 | 2020 | EHD2-mediated restriction of caveolar dynamics regulates cellular fatty acid uptake. | 28 |
| 32945345 | 2020 | TUSC8 inhibits the development of osteosarcoma by sponging miR‑197‑3p and targeting EHD2. | 9 |
| 30811273 | 2019 | EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes. | 14 |
| 30995867 | 2019 | Effect of EH domain containing protein 2 on the biological behavior of clear cell renal cell carcinoma. | 6 |
| 31600286 | 2019 | eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization. | 10 |
| 30811273 | 2019 | EHD2 regulates adipocyte function and is enriched at cell surface-associated lipid droplets in primary human adipocytes. | 14 |
| 30995867 | 2019 | Effect of EH domain containing protein 2 on the biological behavior of clear cell renal cell carcinoma. | 6 |
Citation
Dessen P
EHD2 (EH domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53067/ehd2
