Identity
HGNC
LOCATION
9q34.3
LOCUSID
ALIAS
1-AGPAT2,BSCL,BSCL1,LPAAB,LPAAT-beta
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10555
MIM: 603100
HGNC: 325
Ensembl: ENSG00000169692
Variants:
dbSNP: 10555
ClinVar: 10555
TCGA: ENSG00000169692
COSMIC: AGPAT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34164774 | 2021 | Circular RNA circ-CHI3L1.2 modulates cisplatin resistance of osteosarcoma cells via the miR-340-5p/LPAATβ axis. | 10 |
| 34824276 | 2021 | AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway. | 12 |
| 34164774 | 2021 | Circular RNA circ-CHI3L1.2 modulates cisplatin resistance of osteosarcoma cells via the miR-340-5p/LPAATβ axis. | 10 |
| 34824276 | 2021 | AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway. | 12 |
| 32094408 | 2020 | Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation. | 9 |
| 32117065 | 2020 | Congenital Generalized Lipoatrophy (Berardinelli-Seip Syndrome) Type 1: Description of Novel AGPAT2 Homozygous Variants Showing the Highly Heterogeneous Presentation of the Disease. | 12 |
| 32412105 | 2020 | A rare frameshift mutation in the AGPAT2 gene in a family from gaza with congenital generalized lipodystrophy. | 0 |
| 32094408 | 2020 | Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation. | 9 |
| 32117065 | 2020 | Congenital Generalized Lipoatrophy (Berardinelli-Seip Syndrome) Type 1: Description of Novel AGPAT2 Homozygous Variants Showing the Highly Heterogeneous Presentation of the Disease. | 12 |
| 32412105 | 2020 | A rare frameshift mutation in the AGPAT2 gene in a family from gaza with congenital generalized lipodystrophy. | 0 |
| 29908837 | 2018 | Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia. | 36 |
| 29908837 | 2018 | Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia. | 36 |
| 28035350 | 2017 | Silencing LPAATβ inhibits tumor growth of cisplatin-resistant human osteosarcoma in vivo and in vitro. | 11 |
| 28035350 | 2017 | Silencing LPAATβ inhibits tumor growth of cisplatin-resistant human osteosarcoma in vivo and in vitro. | 11 |
| 24498038 | 2014 | Divergent metabolic phenotype between two sisters with congenital generalized lipodystrophy due to double AGPAT2 homozygous mutations. a clinical, genetic and in silico study. | 8 |
Citation
Dessen P
AGPAT2 (1-acylglycerol-3-phosphate O-acyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53073/agpat2
