Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 134
MIM: 102775
HGNC: 262
Ensembl: ENSG00000163485
Variants:
dbSNP: 134
ClinVar: 134
TCGA: ENSG00000163485
COSMIC: ADORA1
RNA/Proteins
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443450 | Asthma | Disease | ClinicalAnnotation | associated | PD | 19019667 | |
| PA448497 | aspirin | Chemical | ClinicalAnnotation | associated | PD | 19019667 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38508143 | 2024 | Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation. | 0 |
| 38508143 | 2024 | Activation of hepatic adenosine A1 receptor ameliorates MASH via inhibiting SREBPs maturation. | 0 |
| 36637988 | 2023 | Comparative Study of Receptor-, Receptor State-, and Membrane-Dependent Cholesterol Binding Sites in A(2A) and A(1) Adenosine Receptors Using Coarse-Grained Molecular Dynamics Simulations. | 2 |
| 36637988 | 2023 | Comparative Study of Receptor-, Receptor State-, and Membrane-Dependent Cholesterol Binding Sites in A(2A) and A(1) Adenosine Receptors Using Coarse-Grained Molecular Dynamics Simulations. | 2 |
| 35046410 | 2022 | Crystal structure of the α(1B)-adrenergic receptor reveals molecular determinants of selective ligand recognition. | 13 |
| 36279718 | 2022 | The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A(1)-A(2A) receptor heteromer formation and function. | 3 |
| 35046410 | 2022 | Crystal structure of the α(1B)-adrenergic receptor reveals molecular determinants of selective ligand recognition. | 13 |
| 36279718 | 2022 | The ADORA1 mutation linked to early-onset Parkinson's disease alters adenosine A(1)-A(2A) receptor heteromer formation and function. | 3 |
| 32878560 | 2021 | Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women with polycystic ovary syndrome and poor responder who are a candidate for IVF: the novel strategic role of clonidine in this expression. | 2 |
| 33524770 | 2021 | Systematic deletion of adenosine receptors reveals novel roles in inflammation and pyroptosis in THP-1 macrophages. | 4 |
| 33961854 | 2021 | ADORA1 promotes nasopharyngeal carcinoma cell progression through regulation of PI3K/AKT/GSK-3β/β-catenin signaling. | 7 |
| 34536555 | 2021 | Plasmacytoid dendritic cells recruited by HIF-1α/eADO/ADORA1 signaling induce immunosuppression in hepatocellular carcinoma. | 26 |
| 34671682 | 2021 | Adenosine A1 Receptor Deficiency Aggravates Extracellular Matrix Accumulation in Diabetic Nephropathy through Disturbance of Peritubular Microenvironment. | 5 |
| 32878560 | 2021 | Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women with polycystic ovary syndrome and poor responder who are a candidate for IVF: the novel strategic role of clonidine in this expression. | 2 |
| 33524770 | 2021 | Systematic deletion of adenosine receptors reveals novel roles in inflammation and pyroptosis in THP-1 macrophages. | 4 |
Citation
Dessen P
ADORA1 (adenosine A1 receptor)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53078/adora1
