CECR2 (CECR2 histone acetyl-lysine reader)

2012-12-01  

Identity

HGNC
LOCATION
22q11.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 27443
MIM: 607576
HGNC: 1840
Ensembl: ENSG00000099954

Variants:

dbSNP: 27443
ClinVar: 27443
TCGA: ENSG00000099954
COSMIC: CECR2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099954ENST00000262608A0A0R4J2E1
ENSG00000099954ENST00000342247Q9BXF3
ENSG00000099954ENST00000355219H0Y2Z1
ENSG00000099954ENST00000400585B7WPH3
ENSG00000099954ENST00000612582A0A087WT21

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
351080622022CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression.41
351080622022CECR2 drives breast cancer metastasis by promoting NF-κB signaling and macrophage-mediated immune suppression.41
334686472021Discovery of a hidden transient state in all bromodomain families.13
338260832021A novel tumor suppressor CECR2 down regulation links glutamine metabolism contributes tumor growth in laryngeal squamous cell carcinoma.2
334686472021Discovery of a hidden transient state in all bromodomain families.13
338260832021A novel tumor suppressor CECR2 down regulation links glutamine metabolism contributes tumor growth in laryngeal squamous cell carcinoma.2
323566532020NMR Analyses of Acetylated H2A.Z Isoforms Identify Differential Binding Interactions with the Bromodomain of the NURF Nucleosome Remodeling Complex.9
323566532020NMR Analyses of Acetylated H2A.Z Isoforms Identify Differential Binding Interactions with the Bromodomain of the NURF Nucleosome Remodeling Complex.9
263657972015A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.94
263657972015A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.94
223958672012A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family.11
226997522012Genome-wide screen of human bromodomain-containing proteins identifies Cecr2 as a novel DNA damage response protein.15
223958672012A 600 kb triplication in the cat eye syndrome critical region causes anorectal, renal and preauricular anomalies in a three-generation family.11
226997522012Genome-wide screen of human bromodomain-containing proteins identifies Cecr2 as a novel DNA damage response protein.15
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

CECR2 (CECR2 histone acetyl-lysine reader)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53081/cecr2