Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23587
MIM: 615019
HGNC: 30617
Ensembl: ENSG00000170291
Variants:
dbSNP: 23587
ClinVar: 23587
TCGA: ENSG00000170291
COSMIC: ELP5
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447197 | Attention Deficit Disorder with Hyperactivity | Disease | ClinicalAnnotation | associated | PD | 29382897 | |
| PA450464 | methylphenidate | Chemical | ClinicalAnnotation | associated | PD | 29382897 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31792210 | 2019 | Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. | 40 |
| 31792210 | 2019 | Genome-wide CRISPR screen identifies ELP5 as a determinant of gemcitabine sensitivity in gallbladder cancer. | 40 |
| 22854966 | 2012 | DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator. | 27 |
| 22854966 | 2012 | DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator. | 27 |
| 16850183 | 2006 | Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53. | 4 |
| 16850183 | 2006 | Cloning and characterization of the human gene DERP6, which activates transcriptional activities of p53. | 4 |
Citation
Dessen P
ELP5 (elongator acetyltransferase complex subunit 5)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53111/elp5
