Identity
HGNC
LOCATION
10q23.31
LOCUSID
ALIAS
CIG-49,GARG-49,IFI60,IFIT4,IRG2,ISG60,P60,RIG-G,cig41
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3437
MIM: 604650
HGNC: 5411
Ensembl: ENSG00000119917
Variants:
dbSNP: 3437
ClinVar: 3437
TCGA: ENSG00000119917
COSMIC: IFIT3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119917 | ENST00000371811 | O14879 |
| ENSG00000119917 | ENST00000371811 | Q5T765 |
| ENSG00000119917 | ENST00000371818 | O14879 |
| ENSG00000119917 | ENST00000371818 | Q5T765 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37846815 | 2024 | NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis. | 0 |
| 38200280 | 2024 | ETV7 promotes colorectal cancer progression through upregulation of IFIT3. | 0 |
| 38273364 | 2024 | IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway. | 1 |
| 38963029 | 2024 | Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression. | 0 |
| 37846815 | 2024 | NMI promotes tumor progression and gemcitabine resistance in pancreatic cancer via STAT3-IFIT3 axis. | 0 |
| 38200280 | 2024 | ETV7 promotes colorectal cancer progression through upregulation of IFIT3. | 0 |
| 38273364 | 2024 | IFIT3 accelerates the progression of head and neck squamous cell carcinoma by targeting PD-L1 to activate PI3K/AKT signaling pathway. | 1 |
| 38963029 | 2024 | Expression of ISG60 is induced by TLR3 signaling in BEAS‑2B bronchial epithelial cells: Possible involvement in CXCL10 expression. | 0 |
| 37496288 | 2023 | Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3. | 3 |
| 37496288 | 2023 | Lysyl oxidase-like 2 promotes stemness and enhances antitumor effects of gefitinib in head and neck cancer via IFIT1 and IFIT3. | 3 |
| 36314949 | 2022 | IFIT3 Is Increased in Serum from Patients with Chronic Hepatitis B Virus (HBV) Infection and Promotes the Anti-HBV Effect of Interferon Alpha via JAK-STAT2 In Vitro. | 5 |
| 36462134 | 2022 | Evaluation of IFIT3 and ORM1 as Biomarkers for Discriminating Active Tuberculosis from Latent Infection. | 3 |
| 36314949 | 2022 | IFIT3 Is Increased in Serum from Patients with Chronic Hepatitis B Virus (HBV) Infection and Promotes the Anti-HBV Effect of Interferon Alpha via JAK-STAT2 In Vitro. | 5 |
| 36462134 | 2022 | Evaluation of IFIT3 and ORM1 as Biomarkers for Discriminating Active Tuberculosis from Latent Infection. | 3 |
| 34075171 | 2021 | Interferon-induced protein with tetratricopeptide repeats 3 may be a key factor in primary biliary cholangitis. | 6 |
Citation
Dessen P
IFIT3 (interferon induced protein with tetratricopeptide repeats 3)
Atlas Genet Cytogenet Oncol Haematol. 2013-01-01
Online version: http://atlasgeneticsoncology.org/gene/53142/ifit3
