TRPC5 (transient receptor potential cation channel subfamily C member 5)

2013-01-01  

Identity

HGNC
LOCATION
Xq23
LOCUSID
ALIAS
PPP1R159,TRP5
FUSION GENES

Other Information

Locus ID:

NCBI: 7224
MIM: 300334
HGNC: 12337
Ensembl: ENSG00000072315

Variants:

dbSNP: 7224
ClinVar: 7224
TCGA: ENSG00000072315
COSMIC: TRPC5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000072315ENST00000262839Q9UL62

Expression (GTEx)

0
1

Pathways

PathwaySourceExternal ID
Axon guidanceKEGGko04360
Axon guidanceKEGGhsa04360
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351
TRP channelsREACTOMER-HSA-3295583
Developmental BiologyREACTOMER-HSA-1266738
Axon guidanceREACTOMER-HSA-422475
Netrin-1 signalingREACTOMER-HSA-373752
Role of second messengers in netrin-1 signalingREACTOMER-HSA-418890

References

Pubmed IDYearTitleCitations
372789592024MiR-138-5p Inhibits Thyroid Cancer Cell Growth and Stemness by Targeting TRPC5/Wnt/β-Catenin Pathway.0
372789592024MiR-138-5p Inhibits Thyroid Cancer Cell Growth and Stemness by Targeting TRPC5/Wnt/β-Catenin Pathway.0
357621042022Cellular context determines primary characteristics of human TRPC5 as a cold-activated channel.1
357621042022Cellular context determines primary characteristics of human TRPC5 as a cold-activated channel.1
336832002021Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.26
337922542021TRPC5 in cardiovascular diseases.5
338718772021Involvement of TRPC5 channels, inwardly rectifying K(+) channels, PLCβ and PIP(2) in vasopressin-mediated excitation of medial central amygdala neurons.4
339334532021PIP(2) regulation of TRPC5 channel activation and desensitization.17
341992802021Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.4
348990562021Downregulation of TRPC4 and TRPC5 Inhibits Smooth Muscle Cell Proliferation without Affecting Endothelial Cell Proliferation.1
336832002021Structural basis for human TRPC5 channel inhibition by two distinct inhibitors.26
337922542021TRPC5 in cardiovascular diseases.5
338718772021Involvement of TRPC5 channels, inwardly rectifying K(+) channels, PLCβ and PIP(2) in vasopressin-mediated excitation of medial central amygdala neurons.4
339334532021PIP(2) regulation of TRPC5 channel activation and desensitization.17
341992802021Transient Receptor Potential C 1/4/5 Is a Determinant of MTI-101 Induced Calcium Influx and Cell Death in Multiple Myeloma.4

Citation

Dessen P

TRPC5 (transient receptor potential cation channel subfamily C member 5)

Atlas Genet Cytogenet Oncol Haematol. 2013-01-01

Online version: http://atlasgeneticsoncology.org/gene/53145/trpc5