Identity
HGNC
LOCATION
21q22.3
LOCUSID
ALIAS
2-21,C21orf11,C21orf76,ORF9,PANDER,PRED44
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54097
MIM: 608617
HGNC: 1253
Ensembl: ENSG00000183844
Variants:
dbSNP: 54097
ClinVar: 54097
TCGA: ENSG00000183844
COSMIC: FAM3B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000183844 | ENST00000357985 | P58499 |
| ENSG00000183844 | ENST00000398646 | A8MTF8 |
| ENSG00000183844 | ENST00000398647 | P58499 |
| ENSG00000183844 | ENST00000398652 | P58499 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37847647 | 2024 | Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression. | 1 |
| 37847647 | 2024 | Loss of feedback regulation between FAM3B and androgen receptor driving prostate cancer progression. | 1 |
| 37105387 | 2023 | Identification of rare loss-of-function variants in FAM3B associated with non-syndromic orofacial clefts. | 0 |
| 37105387 | 2023 | Identification of rare loss-of-function variants in FAM3B associated with non-syndromic orofacial clefts. | 0 |
| 32442162 | 2020 | Upregulation of FAM3B Promotes Cisplatin Resistance in Gastric Cancer by Inducing Epithelial-Mesenchymal Transition. | 5 |
| 32442162 | 2020 | Upregulation of FAM3B Promotes Cisplatin Resistance in Gastric Cancer by Inducing Epithelial-Mesenchymal Transition. | 5 |
| 30565387 | 2019 | FAM3B promotes progression of oesophageal carcinoma via regulating the AKT-MDM2-p53 signalling axis and the epithelial-mesenchymal transition. | 15 |
| 30982368 | 2019 | Increased pancreatic-derived factor (PANDER) levels in gestational diabetes mellitus. | 3 |
| 30565387 | 2019 | FAM3B promotes progression of oesophageal carcinoma via regulating the AKT-MDM2-p53 signalling axis and the epithelial-mesenchymal transition. | 15 |
| 30982368 | 2019 | Increased pancreatic-derived factor (PANDER) levels in gestational diabetes mellitus. | 3 |
| 29357840 | 2018 | FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-X(L) cell survival genes. | 9 |
| 29357840 | 2018 | FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-X(L) cell survival genes. | 9 |
| 29357840 | 2018 | FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-X(L) cell survival genes. | 9 |
| 29357840 | 2018 | FAM3B/PANDER inhibits cell death and increases prostate tumor growth by modulating the expression of Bcl-2 and Bcl-X(L) cell survival genes. | 9 |
| 28161382 | 2017 | Association of serum pancreatic derived factor (PANDER) with beta-cell dysfunction in type 2 diabetes mellitus. | 5 |
Citation
Dessen P
FAM3B (FAM3 metabolism regulating signaling molecule B)
Atlas Genet Cytogenet Oncol Haematol. 2013-02-01
Online version: http://atlasgeneticsoncology.org/gene/53174/fam3b
