KAZALD1 (Kazal type serine peptidase inhibitor domain 1)

2013-02-01  

Identity

HGNC
KAZALD1
LOCATION
10q24.31
LOCUSID
81621
ALIAS
BONO1,FKSG28,FKSG40,IGFBP-rP10
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81621
MIM: 609208
HGNC: 25460
Ensembl: ENSG00000107821

Variants:

dbSNP: 81621
ClinVar: 81621
TCGA: ENSG00000107821
COSMIC: KAZALD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107821ENST00000370200Q96I82

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
263151102015Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.21
263151102015Comprehensive molecular pathology analysis of small bowel adenocarcinoma reveals novel targets with potential for clinical utility.21
240025812013Epigenetic silencing of KAZALD1 confers a better prognosis and is associated with malignant transformation/progression in glioma.11
240025812013Epigenetic silencing of KAZALD1 confers a better prognosis and is associated with malignant transformation/progression in glioma.11
228368052012Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma.5
228368052012Characterization of DNA hypermethylation in two cases of peritoneal mesothelioma.5
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
163854512006A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.83
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.4
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.4
155555532004Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells.10
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.4
152618382004Bono1: a gene associated with regions of deposition of bone and dentine.4
155555532004Role of a new member of IGFBP superfamily, IGFBP-rP10, in proliferation and differentiation of osteoblastic cells.10

Citation

Dessen P

KAZALD1 (Kazal type serine peptidase inhibitor domain 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-02-01

Online version: http://atlasgeneticsoncology.org/gene/53179