Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1128
MIM: 118510
HGNC: 1950
Ensembl: ENSG00000168539
Variants:
dbSNP: 1128
ClinVar: 1128
TCGA: ENSG00000168539
COSMIC: CHRM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168539 | ENST00000306960 | P11229 |
| ENSG00000168539 | ENST00000306960 | Q53XZ3 |
| ENSG00000168539 | ENST00000536524 | F5GZF8 |
| ENSG00000168539 | ENST00000543973 | P11229 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34806612 | 2022 | Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease. | 3 |
| 36155524 | 2022 | Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) Protein in the Hippocampus and Temporal Cortex of a Subset of Individuals with Alzheimer's Disease, Parkinson's Disease, or Frontotemporal Dementia: Implications for Patient Survival. | 7 |
| 34806612 | 2022 | Muscarinic Receptors Expression in the Peripheral Blood Cells Differentiate Dementia with Lewy Bodies from Alzheimer's Disease. | 3 |
| 36155524 | 2022 | Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) Protein in the Hippocampus and Temporal Cortex of a Subset of Individuals with Alzheimer's Disease, Parkinson's Disease, or Frontotemporal Dementia: Implications for Patient Survival. | 7 |
| 33143542 | 2021 | Contributions of cholinergic receptor muscarinic 1 and CYP1A2 gene variants on the effects of plasma ratio of clozapine/N-desmethylclozapine on working memory in schizophrenia. | 1 |
| 34212451 | 2021 | Muscarinic acetylcholine receptor M1 mutations causing neurodevelopmental disorder and epilepsy. | 3 |
| 33143542 | 2021 | Contributions of cholinergic receptor muscarinic 1 and CYP1A2 gene variants on the effects of plasma ratio of clozapine/N-desmethylclozapine on working memory in schizophrenia. | 1 |
| 34212451 | 2021 | Muscarinic acetylcholine receptor M1 mutations causing neurodevelopmental disorder and epilepsy. | 3 |
| 30623717 | 2020 | Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. | 4 |
| 32097138 | 2020 | Activation of muscarinic acetylcholine receptor 1 promotes invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition. | 4 |
| 32205868 | 2020 | Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis. | 16 |
| 30623717 | 2020 | Pharmacogenetics of tardive dyskinesia in schizophrenia: The role of CHRM1 and CHRM2 muscarinic receptors. | 4 |
| 32097138 | 2020 | Activation of muscarinic acetylcholine receptor 1 promotes invasion of hepatocellular carcinoma by inducing epithelial-mesenchymal transition. | 4 |
| 32205868 | 2020 | Muscarinic receptors promote castration-resistant growth of prostate cancer through a FAK-YAP signaling axis. | 16 |
| 30027929 | 2018 | Muscarinic acetylcholine receptor M1 mediates prostate cancer cell migration and invasion through hedgehog signaling. | 21 |
Citation
Dessen P
CHRM1 (cholinergic receptor muscarinic 1)
Atlas Genet Cytogenet Oncol Haematol. 2013-03-01
Online version: http://atlasgeneticsoncology.org/gene/53220/chrm1
