CYTIP (cytohesin 1 interacting protein)

2013-03-01 Affiliation

Identity

HGNC

CYTIP

LOCATION

2q24.1

LOCUSID

9595

ALIAS

B3-1,CASP,CYBR,CYTHIP,HE,PSCDBP

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9595
MIM: 604448
HGNC: 9506
Ensembl: ENSG00000115165

Variants:

dbSNP: 9595
ClinVar: 9595
TCGA: ENSG00000115165
COSMIC: CYTIP

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000115165	ENST00000264192	O60759
ENSG00000115165	ENST00000418920	C9JSM2
ENSG00000115165	ENST00000435117	C9JNN8
ENSG00000115165	ENST00000439355	C9JRF8
ENSG00000115165	ENST00000457793	F8WF61

Expression (GTEx)

100

150

200

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
25058460	2014	Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in natural killer cells.	1
25058460	2014	Cytohesin-associated scaffolding protein (CASP) is involved in migration and IFN-γ secretion in natural killer cells.	1
23223005	2013	Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.	123
23469018	2013	In human monocyte derived dendritic cells SOCS1 interacting with CYTIP induces the degradation of CYTIP by the proteasome.	0
23223005	2013	Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer.	123
23469018	2013	In human monocyte derived dendritic cells SOCS1 interacting with CYTIP induces the degradation of CYTIP by the proteasome.	0
21562043	2011	Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration.	22
21562043	2011	Infection of dendritic cells with herpes simplex virus type 1 induces rapid degradation of CYTIP, thereby modulating adhesion and migration.	22
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
17577583	2007	Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes.	18
17577583	2007	Sorting nexin 27 interacts with the Cytohesin associated scaffolding protein (CASP) in lymphocytes.	18
16702224	2006	Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.	7
16702224	2006	Cytohesin binder and regulator augments T cell receptor-induced nuclear factor of activated T Cells.AP-1 activation through regulation of the JNK pathway.	7
12052827	2002	The N-terminal coiled coil domain of the cytohesin/ARNO family of guanine nucleotide exchange factors interacts with the scaffolding protein CASP.	22

Citation

Dessen P

CYTIP (cytohesin 1 interacting protein)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53225/gene-fusions/haematological-explorer/case-report-explorer/