MT1M (metallothionein 1M)

2013-03-01  

Identity

HGNC
MT1M
LOCATION
16q13
LOCUSID
4499
ALIAS
MT-1M,MT-IM,MT1,MT1K

Other Information

Locus ID:

NCBI: 4499
MIM: 156357
HGNC: 14296
Ensembl: ENSG00000205364

Variants:

dbSNP: 4499
ClinVar: 4499
TCGA: ENSG00000205364
COSMIC: MT1M

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000205364ENST00000379818Q8N339
ENSG00000205364ENST00000570233H3BUC6

Expression (GTEx)

0
50
100
150
200
250
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Mineral absorptionKEGGko04978
Mineral absorptionKEGGhsa04978
MetabolismREACTOMER-HSA-1430728
Response to metal ionsREACTOMER-HSA-5660526
Metallothioneins bind metalsREACTOMER-HSA-5661231

References

Pubmed IDYearTitleCitations
372767922023MT1M regulates gastric cancer progression and stemness by modulating the Hedgehog pathway protein GLI1.5
372767922023MT1M regulates gastric cancer progression and stemness by modulating the Hedgehog pathway protein GLI1.5
338208822021Metallothionein MT1M Suppresses Carcinogenesis of Esophageal Carcinoma Cells through Inhibition of the Epithelial-Mesenchymal Transition and the SOD1/PI3K Axis.7
338208822021Metallothionein MT1M Suppresses Carcinogenesis of Esophageal Carcinoma Cells through Inhibition of the Epithelial-Mesenchymal Transition and the SOD1/PI3K Axis.7
310023542019DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma.7
310023542019DNA methylation of metallothionein genes is associated with the clinical features of renal cell carcinoma.7
294615972018The effect and mechanism of metallothionein MT1M on hepatocellular carcinoma cell.4
302273282018MiR-545-3p/MT1M axis regulates cell proliferation, invasion and migration in hepatocellular carcinoma.27
294615972018The effect and mechanism of metallothionein MT1M on hepatocellular carcinoma cell.4
302273282018MiR-545-3p/MT1M axis regulates cell proliferation, invasion and migration in hepatocellular carcinoma.27
283804332017Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma.10
283804332017Metallothionein 1M suppresses tumorigenesis in hepatocellular carcinoma.10
276500472016MiR-24-3p enhances cell growth in hepatocellular carcinoma by targeting metallothionein 1M.17
278083712016Low metallothionein 1M expression association with poor hepatocellular carcinoma prognosis after curative resection.4
276500472016MiR-24-3p enhances cell growth in hepatocellular carcinoma by targeting metallothionein 1M.17

Citation

Dessen P

MT1M (metallothionein 1M)

Atlas Genet Cytogenet Oncol Haematol. 2013-03-01

Online version: http://atlasgeneticsoncology.org/gene/53233