HORMAD1 (HORMA domain containing 1)

2013-05-01  

Identity

HGNC
LOCATION
1q21.3
LOCUSID
ALIAS
CT46,NOHMA
FUSION GENES

Other Information

Locus ID:

NCBI: 84072
MIM: 609824
HGNC: 25245
Ensembl: ENSG00000143452

Variants:

dbSNP: 84072
ClinVar: 84072
TCGA: ENSG00000143452
COSMIC: HORMAD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143452ENST00000322343Q86X24
ENSG00000143452ENST00000361824Q86X24
ENSG00000143452ENST00000361824A0A140VKG9
ENSG00000143452ENST00000368987X6R751
ENSG00000143452ENST00000368995Q86X24
ENSG00000143452ENST00000442853X6RG95

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381859612024Expression of HORMAD1 in Chronic Rhinosinusitis and Its Correlation with Inflammatory Factors.0
381859612024Expression of HORMAD1 in Chronic Rhinosinusitis and Its Correlation with Inflammatory Factors.0
365243332023A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest.2
373710972023Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas.1
377945932023Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.1
378381772023The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks.2
365243332023A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest.2
373710972023Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas.1
377945932023Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.1
378381772023The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks.2
340363952021HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.12
340363952021HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.12
301855462018HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.35
303335002018The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells.31
301855462018HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.35

Citation

Dessen P

HORMAD1 (HORMA domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53261/hormad1