SIM1 (SIM bHLH transcription factor 1)

2013-05-01  

Identity

HGNC
LOCATION
6q16.3
LOCUSID
ALIAS
bHLHe14
FUSION GENES

Other Information

Locus ID:

NCBI: 6492
MIM: 603128
HGNC: 10882
Ensembl: ENSG00000112246

Variants:

dbSNP: 6492
ClinVar: 6492
TCGA: ENSG00000112246
COSMIC: SIM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112246ENST00000262901P81133
ENSG00000112246ENST00000369208P81133

Expression (GTEx)

0
1
2
3
4
5
6

References

Pubmed IDYearTitleCitations
385324632024STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma.0
385324632024STIM1/SOX2 proteins are co-expressed in the tumor and microenvironmental stromal cells of pancreatic ductal adenocarcinoma and ampullary carcinoma.0
329326092020Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain.3
329326092020Structural Models for the Dynamic Effects of Loss-of-Function Variants in the Human SIM1 Protein Transcriptional Activation Domain.3
290637192018Aberrant single-minded homolog 1 methylation as a potential biomarker for cervical cancer.9
302974282018Genetic variation in the SIM1 locus is associated with erectile dysfunction.9
290637192018Aberrant single-minded homolog 1 methylation as a potential biomarker for cervical cancer.9
302974282018Genetic variation in the SIM1 locus is associated with erectile dysfunction.9
284721482017Genetic analysis of single-minded 1 gene in early-onset severely obese children and adolescents.3
285939222017Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children.0
284721482017Genetic analysis of single-minded 1 gene in early-onset severely obese children and adolescents.3
285939222017Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children.0
267959562016Copy number variation (CNV) analysis and mutation analysis of the 6q14.1-6q16.3 genes SIM1 and MRAP2 in Prader Willi like patients.11
267959562016Copy number variation (CNV) analysis and mutation analysis of the 6q14.1-6q16.3 genes SIM1 and MRAP2 in Prader Willi like patients.11
253517782015Incomplete penetrance and phenotypic variability of 6q16 deletions including SIM1.12

Citation

Dessen P

SIM1 (SIM bHLH transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-05-01

Online version: http://atlasgeneticsoncology.org/gene/53285/sim1