SPHKAP (SPHK1 interactor, AKAP domain containing)

2003-02-01  

Identity

HGNC
SPHKAP
LOCATION
2q36.3
LOCUSID
80309
ALIAS
SKIP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80309
MIM: 611646
HGNC: 30619
Ensembl: ENSG00000153820

Variants:

dbSNP: 80309
ClinVar: 80309
TCGA: ENSG00000153820
COSMIC: SPHKAP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153820ENST00000344657Q2M3C7
ENSG00000153820ENST00000392056Q2M3C7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
337973812022SphK1 Promotes Cancer Progression through Activating JAK/STAT Pathway and Up-Regulating S1PR1 Expression in Colon Cancer Cells.5
337973812022SphK1 Promotes Cancer Progression through Activating JAK/STAT Pathway and Up-Regulating S1PR1 Expression in Colon Cancer Cells.5
321611162020Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.4
321611162020Repression of sphingosine kinase (SK)-interacting protein (SKIP) in acute myeloid leukemia diminishes SK activity and its re-expression restores SK function.4
224793722012Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.35
224793722012Genome wide analysis of acute myeloid leukemia reveal leukemia specific methylome and subtype specific hypomethylation of repeats.35
220840752011An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.73
220840752011An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.73
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203940972010Sphingosine kinase interacting protein is an A-kinase anchoring protein specific for type I cAMP-dependent protein kinase.46
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203940972010Sphingosine kinase interacting protein is an A-kinase anchoring protein specific for type I cAMP-dependent protein kinase.46
180554542008Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.72
180554542008Sphingosine kinase 1 is up-regulated during hypoxia in U87MG glioma cells. Role of hypoxia-inducible factors 1 and 2.72
171644392007Progesterone-induced sphingosine kinase-1 expression in the rat uterus during pregnancy and signaling consequences.10

Citation

Dessen P

SPHKAP (SPHK1 interactor, AKAP domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/53312/case-report-explorer/css/css/lib/js/lib/jquery-3.5.1.min.js