Identity
HGNC
LOCATION
1p35.3
LOCUSID
ALIAS
6-16,FAM14C,G1P3,IFI-6-16,IFI616
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2537
MIM: 147572
HGNC: 4054
Ensembl: ENSG00000126709
Variants:
dbSNP: 2537
ClinVar: 2537
TCGA: ENSG00000126709
COSMIC: IFI6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000126709 | ENST00000339145 | P09912 |
| ENSG00000126709 | ENST00000361157 | P09912 |
| ENSG00000126709 | ENST00000361157 | A0A348GSI1 |
| ENSG00000126709 | ENST00000362020 | P09912 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36793726 | 2023 | Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation. | 10 |
| 37067145 | 2023 | The role of glucose-dependent insulinotropic polypeptide 3 (G1P-3) and nucleolar phosphoprotein-1 (NPM1) in pathogenesis of psoriasis. | 0 |
| 37661181 | 2023 | Role of interferon alpha-inducible protein 6 in modulating the proliferation, apoptosis and senescence of oesophageal squamous cell carcinoma cells. | 1 |
| 37670388 | 2023 | BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6. | 1 |
| 36793726 | 2023 | Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation. | 10 |
| 37067145 | 2023 | The role of glucose-dependent insulinotropic polypeptide 3 (G1P-3) and nucleolar phosphoprotein-1 (NPM1) in pathogenesis of psoriasis. | 0 |
| 37661181 | 2023 | Role of interferon alpha-inducible protein 6 in modulating the proliferation, apoptosis and senescence of oesophageal squamous cell carcinoma cells. | 1 |
| 37670388 | 2023 | BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6. | 1 |
| 35883685 | 2022 | IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of γ-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement. | 4 |
| 35883685 | 2022 | IDO1, FAT10, IFI6, and GILT Are Involved in the Antiretroviral Activity of γ-Interferon and IDO1 Restricts Retrovirus Infection by Autophagy Enhancement. | 4 |
| 33539340 | 2021 | ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells. | 14 |
| 33868257 | 2021 | The Functional and Antiviral Activity of Interferon Alpha-Inducible IFI6 Against Hepatitis B Virus Replication and Gene Expression. | 24 |
| 33539340 | 2021 | ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells. | 14 |
| 33868257 | 2021 | The Functional and Antiviral Activity of Interferon Alpha-Inducible IFI6 Against Hepatitis B Virus Replication and Gene Expression. | 24 |
| 32727517 | 2020 | IFI6 depletion inhibits esophageal squamous cell carcinoma progression through reactive oxygen species accumulation via mitochondrial dysfunction and endoplasmic reticulum stress. | 37 |
Citation
Dessen P
IFI6 (interferon alpha inducible protein 6)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53345/ifi6
