Identity
HGNC
LOCATION
Xp11.22
LOCUSID
ALIAS
JHDM1F,KDM7B,MRXSSD,ZNF422
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23133
MIM: 300560
HGNC: 20672
Ensembl: ENSG00000172943
Variants:
dbSNP: 23133
ClinVar: 23133
TCGA: ENSG00000172943
COSMIC: PHF8
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36136271 | 2023 | NEDD4L represses prostate cancer cell proliferation via modulating PHF8 through the ubiquitin-proteasome pathway. | 3 |
| 37454216 | 2023 | Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons. | 0 |
| 37469124 | 2023 | Histone demethylase PHF8 facilitates the development of chronic myeloid leukaemia by directly targeting BCR::ABL1. | 0 |
| 37531433 | 2023 | PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma. | 3 |
| 36136271 | 2023 | NEDD4L represses prostate cancer cell proliferation via modulating PHF8 through the ubiquitin-proteasome pathway. | 3 |
| 37454216 | 2023 | Loss of PHF8 induces a viral mimicry response by activating endogenous retrotransposons. | 0 |
| 37469124 | 2023 | Histone demethylase PHF8 facilitates the development of chronic myeloid leukaemia by directly targeting BCR::ABL1. | 0 |
| 37531433 | 2023 | PHF8-GLUL axis in lipid deposition and tumor growth of clear cell renal cell carcinoma. | 3 |
| 35051531 | 2022 | Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics. | 3 |
| 35179962 | 2022 | The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis. | 14 |
| 35051531 | 2022 | Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics. | 3 |
| 35179962 | 2022 | The histone demethylase PHF8 regulates TGFβ signaling and promotes melanoma metastasis. | 14 |
| 33009820 | 2021 | Histone demethylase PHF8 drives neuroendocrine prostate cancer progression by epigenetically upregulating FOXA2. | 24 |
| 34100557 | 2021 | Histone demethylase PHF8 promotes cell growth and metastasis of non-small-cell lung cancer through activating Wnt/β-catenin signaling pathway. | 4 |
| 34356104 | 2021 | Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures. | 14 |
Citation
Dessen P
PHF8 (PHD finger protein 8)
Atlas Genet Cytogenet Oncol Haematol. 2013-06-01
Online version: http://atlasgeneticsoncology.org/gene/53358/phf8
