KIR3DL1 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1)

2013-06-01  

Identity

HGNC
KIR3DL1
LOCATION
19q13.42
LOCUSID
3811
ALIAS
CD158E1,KIR,KIR2DL5B,KIR3DL1/S1,NKAT-3,NKAT3,NKB1,NKB1B

Other Information

Locus ID:

NCBI: 3811
MIM: 604946
HGNC: 6338
Ensembl: ENSG00000167633

Variants:

dbSNP: 3811
ClinVar: 3811
TCGA: ENSG00000167633
COSMIC: KIR3DL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000167633ENST00000326542W5QJC1
ENSG00000167633ENST00000358178P43629
ENSG00000167633ENST00000391728P43629
ENSG00000167633ENST00000391728Q5UCE2

Expression (GTEx)

0
1
2
3
4
5
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Antigen processing and presentationKEGGko04612
Natural killer cell mediated cytotoxicityKEGGko04650
Graft-versus-host diseaseKEGGko05332
Antigen processing and presentationKEGGhsa04612
Natural killer cell mediated cytotoxicityKEGGhsa04650
Graft-versus-host diseaseKEGGhsa05332
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellREACTOMER-HSA-198933

References

Pubmed IDYearTitleCitations
366375132023KIR Allelic Variation and the Remission of Atopic Dermatitis Over Time.0
366897272023Large case-control study indicates no association of KIR genotype and risk of developing acute myeloid leukemia.0
368075372023Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1 gene *007 may modulate disease progression of human immunodeficiency virus-1 infection in the Japanese population.0
368494222023HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19.2
371693132023Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients.1
376472752023Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.0
366375132023KIR Allelic Variation and the Remission of Atopic Dermatitis Over Time.0
366897272023Large case-control study indicates no association of KIR genotype and risk of developing acute myeloid leukemia.0
368075372023Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 1 gene *007 may modulate disease progression of human immunodeficiency virus-1 infection in the Japanese population.0
368494222023HLA-Bw4 in association with KIR3DL1 favors natural killer cell-mediated protection against severe COVID-19.2
371693132023Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients.1
376472752023Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.0
349294142022Association of KIR gene polymorphisms with COVID-19 disease.14
350360932022KIR gene content imputation from single-nucleotide polymorphisms in the Finnish population.1
351926012022Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.6

Citation

Dessen P

KIR3DL1 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53362