BAZ2A (bromodomain adjacent to zinc finger domain 2A)

2013-06-01  

Identity

HGNC
BAZ2A
LOCATION
12q13.3
LOCUSID
11176
ALIAS
TIP5,WALp3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 11176
MIM: 605682
HGNC: 962
Ensembl: ENSG00000076108

Variants:

dbSNP: 11176
ClinVar: 11176
TCGA: ENSG00000076108
COSMIC: BAZ2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000076108ENST00000379441J3KPG5
ENSG00000076108ENST00000546695F8VWQ3
ENSG00000076108ENST00000547453H0YHL2
ENSG00000076108ENST00000547650H0YII3
ENSG00000076108ENST00000549506F8W053
ENSG00000076108ENST00000549787A0A0C4DGI9
ENSG00000076108ENST00000549884F8VU39
ENSG00000076108ENST00000551812Q9UIF9
ENSG00000076108ENST00000551996H0YHQ7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
Negative epigenetic regulation of rRNA expressionREACTOMER-HSA-5250941
NoRC negatively regulates rRNA expressionREACTOMER-HSA-427413

References

Pubmed IDYearTitleCitations
379258112024Nasopharyngeal carcinoma derived exosomes regulate the proliferation and migration of nasopharyngeal carcinoma cells by mediating the miR-99a-5p BAZ2A axis.0
384332772024Pan-cancer and multi-omics analyses revealed the diagnostic and prognostic value of BAZ2A in liver cancer.0
379258112024Nasopharyngeal carcinoma derived exosomes regulate the proliferation and migration of nasopharyngeal carcinoma cells by mediating the miR-99a-5p BAZ2A axis.0
384332772024Pan-cancer and multi-omics analyses revealed the diagnostic and prognostic value of BAZ2A in liver cancer.0
371846612023BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer.0
371846612023BAZ2A-RNA mediated association with TOP2A and KDM1A represses genes implicated in prostate cancer.0
344031952021BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.15
347151262021Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.4
344031952021BAZ2A-mediated repression via H3K14ac-marked enhancers promotes prostate cancer stem cells.15
347151262021Structural basis of the TAM domain of BAZ2A in binding to DNA or RNA independent of methylation status.4
296201862018The transcription factor 7 like 2‑binding protein TIP5 activates β‑catenin/transcription factor signaling in hepatocellular carcinoma.9
296201862018The transcription factor 7 like 2‑binding protein TIP5 activates β‑catenin/transcription factor signaling in hepatocellular carcinoma.9
283418092017Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.20
283418092017Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.20
252167002015Protein deep sequencing applied to biobank samples from patients with pancreatic cancer.24

Citation

Dessen P

BAZ2A (bromodomain adjacent to zinc finger domain 2A)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53416/gene-explorer/img/favicon/favicon-16x16.png