FNBP1L (formin binding protein 1 like)

2013-09-01  

Identity

HGNC
FNBP1L
LOCATION
1p22.1
LOCUSID
54874
ALIAS
C1orf39,TOCA1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 54874
MIM: 608848
HGNC: 20851
Ensembl: ENSG00000137942

Variants:

dbSNP: 54874
ClinVar: 54874
TCGA: ENSG00000137942
COSMIC: FNBP1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137942ENST00000260506Q5T0N5
ENSG00000137942ENST00000271234Q5T0N5
ENSG00000137942ENST00000370253Q5T0N5
ENSG00000137942ENST00000424449A0A075B6Q2
ENSG00000137942ENST00000604705S4R347

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Clathrin-mediated endocytosisREACTOMER-HSA-8856828

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
294888642018Identification of interactions among host and bacterial proteins and evaluation of their role early during Shigella flexneri infection.7
294888642018Identification of interactions among host and bacterial proteins and evaluation of their role early during Shigella flexneri infection.7
271292012016Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.15
271292012016Investigation of the Interaction between Cdc42 and Its Effector TOCA1: HANDOVER OF Cdc42 TO THE ACTIN REGULATOR N-WASP IS FACILITATED BY DIFFERENTIAL BINDING AFFINITIES.15
233581562014Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.123
255471742014Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.11
233581562014Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.123
255471742014Toca-1 is suppressed by p53 to limit breast cancer cell invasion and tumor metastasis.11
228247982013Transducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.20
228247982013Transducer of Cdc42-dependent actin assembly promotes breast cancer invasion and metastasis.20
210627392011Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness.25
210627392011Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness.25
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
207301032010Cdc42 interaction with N-WASP and Toca-1 regulates membrane tubulation, vesicle formation and vesicle motility: implications for endocytosis.34
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

FNBP1L (formin binding protein 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53509