H1-5 (H1.5 linker histone, cluster member)

2013-09-01  

Identity

HGNC
LOCATION
6p22.1
LOCUSID
ALIAS
H1,H1.5,H1B,H1F5,H1s-3,HIST1H1B

Other Information

Locus ID:

NCBI: 3009
MIM: 142711
HGNC: 4719
Ensembl: ENSG00000184357

Variants:

dbSNP: 3009
ClinVar: 3009
TCGA: ENSG00000184357
COSMIC: H1-5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000184357ENST00000331442P16401

Pathways

PathwaySourceExternal ID
Programmed Cell DeathREACTOMER-HSA-5357801
ApoptosisREACTOMER-HSA-109581
Apoptotic execution phaseREACTOMER-HSA-75153
Apoptosis induced DNA fragmentationREACTOMER-HSA-140342
Activation of DNA fragmentation factorREACTOMER-HSA-211227
Cellular responses to stressREACTOMER-HSA-2262752
Cellular SenescenceREACTOMER-HSA-2559583
DNA Damage/Telomere Stress Induced SenescenceREACTOMER-HSA-2559586
Formation of Senescence-Associated Heterochromatin Foci (SAHF)REACTOMER-HSA-2559584

References

Pubmed IDYearTitleCitations
332213352021Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin.6
332213352021Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin.6
330280272020How Human H1 Histone Recognizes DNA.3
330280272020How Human H1 Histone Recognizes DNA.3
310767402019Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing.8
310767402019Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing.8
244350472014Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.97
247847182014Immunohistochemical detection of promyelocytic leukemia zinc finger and histone 1.5 in uterine leiomyosarcoma and leiomyoma.5
250237632014Expression of H1.5 and PLZF in granulosa cell tumors and normal ovarian tissues: a short report.2
244350472014Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.97
247847182014Immunohistochemical detection of promyelocytic leukemia zinc finger and histone 1.5 in uterine leiomyosarcoma and leiomyoma.5
250237632014Expression of H1.5 and PLZF in granulosa cell tumors and normal ovarian tissues: a short report.2
234160302013Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study.10
234160302013Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study.10
216548452011FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity.13

Citation

Dessen P

H1-5 (H1.5 linker histone, cluster member)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53525/js/lib/gene-fusions-explorer/meetings/