H1-5 (H1.5 linker histone, cluster member)

H1-5 (H1.5 linker histone, cluster member)

2013-09-01 Affiliation

Identity

HGNC

LOCATION

6p22.1

LOCUSID

ALIAS

H1,H1.5,H1B,H1F5,H1s-3,HIST1H1B

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 3009
MIM: 142711
HGNC: 4719
Ensembl: ENSG00000184357

Variants:

dbSNP: 3009
ClinVar: 3009
TCGA: ENSG00000184357
COSMIC: H1-5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000184357	ENST00000331442	P16401

Pathways

Pathway	Source	External ID
Programmed Cell Death	REACTOME	R-HSA-5357801
Apoptosis	REACTOME	R-HSA-109581
Apoptotic execution phase	REACTOME	R-HSA-75153
Apoptosis induced DNA fragmentation	REACTOME	R-HSA-140342
Activation of DNA fragmentation factor	REACTOME	R-HSA-211227
Cellular responses to stress	REACTOME	R-HSA-2262752
Cellular Senescence	REACTOME	R-HSA-2559583
DNA Damage/Telomere Stress Induced Senescence	REACTOME	R-HSA-2559586
Formation of Senescence-Associated Heterochromatin Foci (SAHF)	REACTOME	R-HSA-2559584

References

Pubmed ID	Year	Title	Citations
33221335	2021	Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin.	6
33221335	2021	Nano-Surveillance: Tracking Individual Molecules in a Sea of Chromatin.	6
33028027	2020	How Human H1 Histone Recognizes DNA.	3
33028027	2020	How Human H1 Histone Recognizes DNA.	3
31076740	2019	Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing.	8
31076740	2019	Histone H1.5 binds over splice sites in chromatin and regulates alternative splicing.	8
24435047	2014	Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.	97
24784718	2014	Immunohistochemical detection of promyelocytic leukemia zinc finger and histone 1.5 in uterine leiomyosarcoma and leiomyoma.	5
25023763	2014	Expression of H1.5 and PLZF in granulosa cell tumors and normal ovarian tissues: a short report.	2
24435047	2014	Mutations in linker histone genes HIST1H1 B, C, D, and E; OCT2 (POU2F2); IRF8; and ARID1A underlying the pathogenesis of follicular lymphoma.	97
24784718	2014	Immunohistochemical detection of promyelocytic leukemia zinc finger and histone 1.5 in uterine leiomyosarcoma and leiomyoma.	5
25023763	2014	Expression of H1.5 and PLZF in granulosa cell tumors and normal ovarian tissues: a short report.	2
23416030	2013	Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study.	10
23416030	2013	Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors: a pilot immunohistochemical study.	10
21654845	2011	FoxP3 interacts with linker histone H1.5 to modulate gene expression and program Treg cell activity.	13

Citation

Dessen P

H1-5 (H1.5 linker histone, cluster member)

Atlas Genet Cytogenet Oncol Haematol. 2013-09-01

Online version: http://atlasgeneticsoncology.org/gene/53525/meetings/favicon/js/web-card-gene.js