ZNF281 (zinc finger protein 281)

2014-02-01  

Identity

HGNC
ZNF281
LOCATION
1q32.1
LOCUSID
23528
ALIAS
GZP1,ZBP-99,ZBP99,ZNP-99
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23528
MIM: 618703
HGNC: 13075
Ensembl: ENSG00000162702

Variants:

dbSNP: 23528
ClinVar: 23528
TCGA: ENSG00000162702
COSMIC: ZNF281

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162702ENST00000294740Q9Y2X9
ENSG00000162702ENST00000367352Q9Y2X9
ENSG00000162702ENST00000367353Q9Y2X9

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
361421692022ZNF281 Promotes Colon Fibroblast Activation in TGFβ1-Induced Gut Fibrosis.4
364384992022Cancer-associated fibroblasts facilitate premetastatic niche formation through lncRNA SNHG5-mediated angiogenesis and vascular permeability in breast cancer.21
361421692022ZNF281 Promotes Colon Fibroblast Activation in TGFβ1-Induced Gut Fibrosis.4
364384992022Cancer-associated fibroblasts facilitate premetastatic niche formation through lncRNA SNHG5-mediated angiogenesis and vascular permeability in breast cancer.21
346049532021Cervical carcinoma progression is aggravated by lncRNA ZNF281 by binding KLF15.2
346049532021Cervical carcinoma progression is aggravated by lncRNA ZNF281 by binding KLF15.2
315707882020ZNF281 is recruited on DNA breaks to facilitate DNA repair by non-homologous end joining.19
317828842020ZNF281/Zfp281 is a target of miR-1 and counteracts muscle differentiation.8
320738962020LncRNA-ZNF281 Interacts with miR-539 to Promote Hepatocellular Carcinoma Cell Invasion and Migration.3
315707882020ZNF281 is recruited on DNA breaks to facilitate DNA repair by non-homologous end joining.19
317828842020ZNF281/Zfp281 is a target of miR-1 and counteracts muscle differentiation.8
320738962020LncRNA-ZNF281 Interacts with miR-539 to Promote Hepatocellular Carcinoma Cell Invasion and Migration.3
311120172019ZNF281 Regulates Cell Proliferation, Migration and Invasion in Colorectal Cancer through Wnt/β-Catenin Signaling.21
312438842019CircAGFG1 sponges miR-203 to promote EMT and metastasis of non-small-cell lung cancer by upregulating ZNF281 expression.30
311120172019ZNF281 Regulates Cell Proliferation, Migration and Invasion in Colorectal Cancer through Wnt/β-Catenin Signaling.21

Citation

Dessen P

ZNF281 (zinc finger protein 281)

Atlas Genet Cytogenet Oncol Haematol. 2014-02-01

Online version: http://atlasgeneticsoncology.org/gene/53710