TRIM11 (tripartite motif containing 11)

2014-01-01  

Identity

HGNC
TRIM11
LOCATION
1q42.13
LOCUSID
81559
ALIAS
BIA1,RNF92
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81559
MIM: 607868
HGNC: 16281
Ensembl: ENSG00000154370

Variants:

dbSNP: 81559
ClinVar: 81559
TCGA: ENSG00000154370
COSMIC: TRIM11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000154370ENST00000284551Q96F44
ENSG00000154370ENST00000366699Q96F44
ENSG00000154370ENST00000493030R4GMV1
ENSG00000154370ENST00000602308R4GNC3
ENSG00000154370ENST00000602582R4GNB9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Adaptive Immune SystemREACTOMER-HSA-1280218
Class I MHC mediated antigen processing & presentationREACTOMER-HSA-983169
Antigen processing: Ubiquitination & Proteasome degradationREACTOMER-HSA-983168

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
363765372023TRIM11, a new target of p53, facilitates the migration and invasion of nasopharyngeal carcinoma cells.1
372486112023TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.0
374990372023TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.11
376042032023TRIM11 promotes cell proliferation of non-small cell lung cancer through the inhibition of ferroptosis by AMPK.1
378045072023TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2.0
363765372023TRIM11, a new target of p53, facilitates the migration and invasion of nasopharyngeal carcinoma cells.1
372486112023TRIM11 Posttranscriptionally Modulated by miR-5193 Facilitates Tumor Growth and Metastasis of Prostate Cancer.0
374990372023TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.11
376042032023TRIM11 promotes cell proliferation of non-small cell lung cancer through the inhibition of ferroptosis by AMPK.1
378045072023TRIM11 attenuates Treg cell differentiation by p62-selective autophagic degradation of AIM2.0
346940312022Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.5
347676732022Tripartite motif-containing protein 11 promotes hepatocellular carcinogenesis through ubiquitin-proteasome-mediated degradation of pleckstrin homology domain leucine-rich repeats protein phosphatase 1.7
356118282022Sex-determining Region Y-box transcription factor 13 promotes breast cancer cell proliferation and glycolysis by activating the tripartite motif containing 11-mediated Wnt/β-catenin signaling pathway.2
359935782022Cutaneous Melanocytic Tumor With CRTC1::TRIM11 Translocation : An Emerging Entity Analyzed in a Series of 41 Cases.3
346940312022Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.5

Citation

Dessen P

TRIM11 (tripartite motif containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-01-01

Online version: http://atlasgeneticsoncology.org/gene/53786/cancer-prone-explorer/favicon/favicon-16x16.png