ATG9A (autophagy related 9A)

2014-02-01  

Identity

HGNC
ATG9A
LOCATION
2q35
LOCUSID
79065
ALIAS
APG9L1,MGD3208,mATG9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79065
MIM: 612204
HGNC: 22408
Ensembl: ENSG00000198925

Variants:

dbSNP: 79065
ClinVar: 79065
TCGA: ENSG00000198925
COSMIC: ATG9A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198925ENST00000361242Q7Z3C6
ENSG00000198925ENST00000361242A0A024R438
ENSG00000198925ENST00000396761Q7Z3C6
ENSG00000198925ENST00000396761A0A024R438
ENSG00000198925ENST00000409033Q7Z3C6
ENSG00000198925ENST00000409422Q7Z3C6
ENSG00000198925ENST00000409618Q7Z3C6
ENSG00000198925ENST00000409618A0A024R438
ENSG00000198925ENST00000412355F2Z3I6
ENSG00000198925ENST00000428226C9JKV7
ENSG00000198925ENST00000429920H7C1G6
ENSG00000198925ENST00000431715C9JD65
ENSG00000198925ENST00000432520C9IYZ9
ENSG00000198925ENST00000434939C9JS65
ENSG00000198925ENST00000436856C9JXG2
ENSG00000198925ENST00000439812C9JX27
ENSG00000198925ENST00000443140C9JFV2
ENSG00000198925ENST00000456708F2Z3I6
ENSG00000198925ENST00000457841C9JDK4

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Autophagy - animalKEGGko04140
Autophagy - animalKEGGhsa04140
Cellular responses to stressREACTOMER-HSA-2262752
MacroautophagyREACTOMER-HSA-1632852
Mitophagy - animalKEGGko04137
Mitophagy - animalKEGGhsa04137
Autophagy - otherKEGGko04136
Autophagy - otherKEGGhsa04136

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
374053802024Tracking the transition from an ATG9A vesicle to an autophagosome.0
379381702024ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A.0
382280362024NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.2
374053802024Tracking the transition from an ATG9A vesicle to an autophagosome.0
379381702024ATG9B is a tissue-specific homotrimeric lipid scramblase that can compensate for ATG9A.0
382280362024NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.2
368922222023A novel role of ATG9A and RB1CC1/FIP200 in mediating cell-death checkpoints to repress TNF cytotoxicity.0
371151572023Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation.17
377827562023ATG9A modulated by miR-195-5p can boost the malignant progression of cervical cancer cells.1
368922222023A novel role of ATG9A and RB1CC1/FIP200 in mediating cell-death checkpoints to repress TNF cytotoxicity.0
371151572023Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation.17
377827562023ATG9A modulated by miR-195-5p can boost the malignant progression of cervical cancer cells.1
351802892022The core autophagy protein ATG9A controls dynamics of cell protrusions and directed migration.9
352493462022Ultrasound cardiogram-based diagnosis of cardiac hypertrophy from hypertension and analysis of its relationship with expression of autophagy-related protein.1
363435732022Atg9A-mediated mitophagy is required for decidual differentiation of endometrial stromal cells.0

Citation

Dessen P

ATG9A (autophagy related 9A)

Atlas Genet Cytogenet Oncol Haematol. 2014-02-01

Online version: http://atlasgeneticsoncology.org/gene/53804