ADGRF5 (adhesion G protein-coupled receptor F5)

2014-05-01  

Identity

HGNC
ADGRF5
LOCATION
6p12.3
LOCUSID
221395
ALIAS
GPR116,KPG_001
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 221395
HGNC: 19030
Ensembl: ENSG00000069122

Variants:

dbSNP: 221395
ClinVar: 221395
TCGA: ENSG00000069122
COSMIC: ADGRF5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000069122ENST00000265417Q8IZF2
ENSG00000069122ENST00000283296Q8IZF2

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Surfactant metabolismREACTOMER-HSA-5683826

References

Pubmed IDYearTitleCitations
389374352024The adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated antitumorigenic effects.0
390019442024GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress.0
389374352024The adhesion-GPCR ADGRF5 fuels breast cancer progression by suppressing the MMP8-mediated antitumorigenic effects.0
390019442024GPR116 alleviates acetaminophen-induced liver injury in mice by inhibiting endoplasmic reticulum stress.0
368783032023The clinical relevance of the adhesion G protein-coupled receptor F5 for human diseases and cancers.2
368783032023The clinical relevance of the adhesion G protein-coupled receptor F5 for human diseases and cancers.2
364971322022The Expression Pattern of Adhesion G Protein-Coupled Receptor F5 Is Related to Cell Adhesion and Metastatic Pathways in Colorectal Cancer-Comprehensive Study Based on In Silico Analysis.4
364971322022The Expression Pattern of Adhesion G Protein-Coupled Receptor F5 Is Related to Cell Adhesion and Metastatic Pathways in Colorectal Cancer-Comprehensive Study Based on In Silico Analysis.4
340169662021Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.17
340169662021Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue.17
320472332020Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors".3
330046242020Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion.19
320472332020Recurrent novel THBS1-ADGRF5 gene fusion in a new tumor subtype "Acral FibroChondroMyxoid Tumors".3
330046242020Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion.19
313641122019MiR-511-5p functions as a tumor suppressor and a predictive of prognosis in colorectal cancer by directly targeting GPR116.13

Citation

Dessen P

ADGRF5 (adhesion G protein-coupled receptor F5)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53899