ZMYND11 (zinc finger MYND-type containing 11)

2014-05-01  

Identity

HGNC
ZMYND11
LOCATION
10p15.3
LOCUSID
10771
ALIAS
BRAM1,BS69,MRD30
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10771
MIM: 608668
HGNC: 16966
Ensembl: ENSG00000015171

Variants:

dbSNP: 10771
ClinVar: 10771
TCGA: ENSG00000015171
COSMIC: ZMYND11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000015171ENST00000309776B7Z2J6
ENSG00000015171ENST00000381584J3QKD2
ENSG00000015171ENST00000381591Q15326
ENSG00000015171ENST00000381604A0A0A0MRY2
ENSG00000015171ENST00000381607Q15326
ENSG00000015171ENST00000397955E7EV75
ENSG00000015171ENST00000397959Q15326
ENSG00000015171ENST00000397962Q15326
ENSG00000015171ENST00000402736E7ENI9
ENSG00000015171ENST00000403354B0QZE2
ENSG00000015171ENST00000439456E9PE09
ENSG00000015171ENST00000509513Q15326
ENSG00000015171ENST00000558098Q15326
ENSG00000015171ENST00000602682Q15326
ENSG00000015171ENST00000627286J3QKD2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
325129762022MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.1
357050312022Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.2
325129762022MicroRNA-196b promotes cell growth and metastasis of ovarian cancer by targeting ZMYND11.1
357050312022Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.2
335940722021ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.17
342160162021ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.3
335940722021ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.17
342160162021ZMYND11 variants are a novel cause of centrotemporal and generalised epilepsies with neurodevelopmental disorder.3
320975282020ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.8
320975282020ZMYND11-related syndromic intellectual disability: 16 patients delineating and expanding the phenotypic spectrum.8
312837822019Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.15
312837822019Increased association between Epstein-Barr virus EBNA2 from type 2 strains and the transcriptional repressor BS69 restricts EBNA2 activity.15
304694732018The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species.5
304694732018The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species.5
281194152017Interaction with ZMYND11 mediates opposing roles of Ras-responsive transcription factors ETS1 and ETS2.11

Citation

Dessen P

ZMYND11 (zinc finger MYND-type containing 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-05-01

Online version: http://atlasgeneticsoncology.org/gene/53916/gene-fusions-explorer/gene-fusions-explorer/js/lib/bootstrap.min.js