DUSP15 (dual specificity phosphatase 15)

2014-06-01  

Identity

HGNC
DUSP15
LOCATION
20q11.21
LOCUSID
128853
ALIAS
C20orf57,VHY

Other Information

Locus ID:

NCBI: 128853
MIM: 616776
HGNC: 16236
Ensembl: ENSG00000149599

Variants:

dbSNP: 128853
ClinVar: 128853
TCGA: ENSG00000149599
COSMIC: DUSP15

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000149599ENST00000278979Q9H1R2
ENSG00000149599ENST00000339738Q9H1R2
ENSG00000149599ENST00000375966Q9H1R2
ENSG00000149599ENST00000398083Q9H1R2
ENSG00000149599ENST00000398084Q9H1R2
ENSG00000149599ENST00000428829Q5QP64
ENSG00000149599ENST00000447647H0Y5A2
ENSG00000149599ENST00000486996Q9H1R2

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
334172242021Dual-Specificity Phosphatase 15 (DUSP15) Modulates Notch Signaling by Enhancing the Stability of Notch Protein.0
342577392021Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder.5
334172242021Dual-Specificity Phosphatase 15 (DUSP15) Modulates Notch Signaling by Enhancing the Stability of Notch Protein.0
342577392021Association between Genetic Variants in DUSP15, CNTNAP2, and PCDHA Genes and Risk of Childhood Autism Spectrum Disorder.5
272236452017Association of oligodendrocytes differentiation regulator gene DUSP15 with autism.7
272236452017Association of oligodendrocytes differentiation regulator gene DUSP15 with autism.7
227923342012Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach.11
227923342012Identification of VHY/Dusp15 as a regulator of oligodendrocyte differentiation through a systematic genomics approach.11
161708012005Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase.3
161708012005Crystal structure of the catalytic domain of human VHY, a dual-specificity protein phosphatase.3
151382522004VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.8
151382522004VHY, a novel myristoylated testis-restricted dual specificity protein phosphatase related to VHX.8

Citation

Dessen P

DUSP15 (dual specificity phosphatase 15)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53941/gene-explorer/cancer-prone-explorer/