RPS19BP1 (ribosomal protein S19 binding protein 1)

2014-06-01  

Identity

HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
AROS,S19BP
FUSION GENES

Other Information

Locus ID:

NCBI: 91582
MIM: 610225
HGNC: 28749
Ensembl: ENSG00000187051

Variants:

dbSNP: 91582
ClinVar: 91582
TCGA: ENSG00000187051
COSMIC: RPS19BP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187051ENST00000334678Q86WX3
ENSG00000187051ENST00000334678A0A024R1T1
ENSG00000187051ENST00000420879F8WFE7

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
Cellular responses to stressREACTOMER-HSA-2262752
Cellular response to heat stressREACTOMER-HSA-3371556
Regulation of HSF1-mediated heat shock responseREACTOMER-HSA-3371453

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
363615572022Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein.1
363615572022Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein.1
297338582018The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection.8
297338582018The Legionella pneumophila Methyltransferase RomA Methylates Also Non-histone Proteins during Infection.8
263391642015AROS Is a Significant Biomarker for Tumor Aggressiveness in Non-cirrhotic Hepatocellular Carcinoma.2
263391642015AROS Is a Significant Biomarker for Tumor Aggressiveness in Non-cirrhotic Hepatocellular Carcinoma.2
246810972014AROS has a context-dependent effect on SIRT1.8
246810972014AROS has a context-dependent effect on SIRT1.8
233498632013The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response.25
235483082013Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.18
242582752013Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity.16
233498632013The SIRT1 modulators AROS and DBC1 regulate HSF1 activity and the heat shock response.25
235483082013Molecular architecture of the human protein deacetylase Sirt1 and its regulation by AROS and resveratrol.18
242582752013Active regulator of SIRT1 is required for cancer cell survival but not for SIRT1 activity.16
179642662007Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.197

Citation

Dessen P

RPS19BP1 (ribosomal protein S19 binding protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-06-01

Online version: http://atlasgeneticsoncology.org/gene/53979/tumors-explorer/css/gene-fusions/?id=53979