ACAD11 (acyl-CoA dehydrogenase family member 11)

2014-08-01  

Identity

HGNC
ACAD11
LOCATION
3q22.1
LOCUSID
84129
ALIAS
ACAD-11
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 84129
MIM: 614288
HGNC: 30211
Ensembl: ENSG00000240303

Variants:

dbSNP: 84129
ClinVar: 84129
TCGA: ENSG00000240303
COSMIC: ACAD11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000240303ENST00000264990Q709F0
ENSG00000240303ENST00000481970D6RDI8
ENSG00000240303ENST00000485198F8WEV0
ENSG00000240303ENST00000510100H0Y9C6

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Mitochondrial Fatty Acid Beta-OxidationREACTOMER-HSA-77289

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
257048132015Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.35
257048132015Analysis of p53 transactivation domain mutants reveals Acad11 as a metabolic target important for p53 pro-survival function.35
212376832011Identification and characterization of new long chain acyl-CoA dehydrogenases.42
212376832011Identification and characterization of new long chain acyl-CoA dehydrogenases.42
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
204069642010Risk of meningioma and common variation in genes related to innate immunity.21
204387852010Polymorphisms in innate immunity genes and risk of childhood leukemia.12
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35
194235402009Common variation in genes related to innate immunity and risk of adult glioma.35

Citation

Dessen P

ACAD11 (acyl-CoA dehydrogenase family member 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54100/cancer-prone-explorer/case-report-explorer/css/lib/bootstrap.min.css