CA7 (carbonic anhydrase 7)

2014-08-01  

Identity

HGNC
CA7
LOCATION
16q22.1
LOCUSID
766
ALIAS
CA-VII,CAVII
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 766
MIM: 114770
HGNC: 1381
Ensembl: ENSG00000168748

Variants:

dbSNP: 766
ClinVar: 766
TCGA: ENSG00000168748
COSMIC: CA7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000168748ENST00000338437P43166
ENSG00000168748ENST00000394069P43166
ENSG00000168748ENST00000548332F8W0L0

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Nitrogen metabolismKEGGko00910
Nitrogen metabolismKEGGhsa00910
MetabolismREACTOMER-HSA-1430728
Reversible hydration of carbon dioxideREACTOMER-HSA-1475029

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
378951852023Unlocking the Potential of the CA2, CA7, and ITM2C Gene Signatures for the Early Detection of Colorectal Cancer: A Comprehensive Analysis of RNA-Seq Data by Utilizing Machine Learning Algorithms.3
378951852023Unlocking the Potential of the CA2, CA7, and ITM2C Gene Signatures for the Early Detection of Colorectal Cancer: A Comprehensive Analysis of RNA-Seq Data by Utilizing Machine Learning Algorithms.3
276886582016Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas.26
276886582016Carbonic anhydrase enzymes II, VII, IX and XII in colorectal carcinomas.26
258858982015Prognostic value of carbonic anhydrase VII expression in colorectal carcinoma.16
258858982015Prognostic value of carbonic anhydrase VII expression in colorectal carcinoma.16
238515722013Human carbonic anhydrase VII protects cells from oxidative damage.13
238515722013Human carbonic anhydrase VII protects cells from oxidative damage.13
204939212010Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme.12
204939212010Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme.12
155282362005Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII.153
156868952005Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.16
155282362005Two developmental switches in GABAergic signalling: the K+-Cl- cotransporter KCC2 and carbonic anhydrase CAVII.153
156868952005Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.16

Citation

Dessen P

CA7 (carbonic anhydrase 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54187