CASP12 (caspase 12 (gene/pseudogene))

2014-08-01  

Identity

HGNC
CASP12
LOCATION
11q22.3
LOCUSID
100506742
ALIAS
CASP-12,CASP12P1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 100506742
MIM: 608633
HGNC: 19004
Ensembl: ENSG00000204403

Variants:

dbSNP: 100506742
ClinVar: 100506742
TCGA: ENSG00000204403
COSMIC: CASP12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204403ENST00000417998Q6UXS9
ENSG00000204403ENST00000422698A0A384DVP2
ENSG00000204403ENST00000458137Q6UXS9

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
ApoptosisKEGGko04210
Alzheimer's diseaseKEGGko05010
Amyotrophic lateral sclerosis (ALS)KEGGko05014
ApoptosisKEGGhsa04210
Alzheimer's diseaseKEGGhsa05010
Amyotrophic lateral sclerosis (ALS)KEGGhsa05014
Prion diseasesKEGGko05020
Prion diseasesKEGGhsa05020
NOD-like receptor signaling pathwayKEGGko04621
NOD-like receptor signaling pathwayKEGGhsa04621
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Hepatitis BKEGGhsa05161

References

Pubmed IDYearTitleCitations
339247552021Human Caspase 12 Enhances NF-κB Activity through Activation of IKK in Nasopharyngeal Carcinoma Cells.4
339247552021Human Caspase 12 Enhances NF-κB Activity through Activation of IKK in Nasopharyngeal Carcinoma Cells.4
315578822019Common Nevus and Skin Cutaneous Melanoma: Prognostic Genes Identified by Gene Co-Expression Network Analysis.16
318046772019Analysis of CASP12 diagnostic and prognostic values in cervical cancer based on TCGA database.1
315578822019Common Nevus and Skin Cutaneous Melanoma: Prognostic Genes Identified by Gene Co-Expression Network Analysis.16
318046772019Analysis of CASP12 diagnostic and prognostic values in cervical cancer based on TCGA database.1
283804442017Caspase 12 degrades IκBα protein and enhances MMP-9 expression in human nasopharyngeal carcinoma cell invasion.7
283804442017Caspase 12 degrades IκBα protein and enhances MMP-9 expression in human nasopharyngeal carcinoma cell invasion.7
265829492016Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.7
269730912016The anti-inflammatory CASPASE-12 gene does not influence SLE phenotype in African-Americans.0
271303682016Calpain and Caspase-12 Expression in Lens Epithelial Cells of Diabetic Cataracts.5
265829492016Caspase-12, but Not Caspase-11, Inhibits Obesity and Insulin Resistance.7
269730912016The anti-inflammatory CASPASE-12 gene does not influence SLE phenotype in African-Americans.0
271303682016Calpain and Caspase-12 Expression in Lens Epithelial Cells of Diabetic Cataracts.5
262615842015ER stress related factor ATF6 and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.19

Citation

Dessen P

CASP12 (caspase 12 (gene/pseudogene))

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54191/tumors-explorer/haematological-explorer/css/card-gene.css