CHID1 (chitinase domain containing 1)

2014-08-01  

Identity

HGNC
CHID1
LOCATION
11p15.5
LOCUSID
66005
ALIAS
GL008,SI-CLP,SICLP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 66005
MIM: 615692
HGNC: 28474
Ensembl: ENSG00000177830

Variants:

dbSNP: 66005
ClinVar: 66005
TCGA: ENSG00000177830
COSMIC: CHID1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000177830ENST00000323578Q9BWS9
ENSG00000177830ENST00000429789Q9BWS9
ENSG00000177830ENST00000436108Q9BWS9
ENSG00000177830ENST00000449825Q9BWS9
ENSG00000177830ENST00000454838Q9BWS9
ENSG00000177830ENST00000525225E9PKF1
ENSG00000177830ENST00000525840E9PJ91
ENSG00000177830ENST00000528154E9PJL0
ENSG00000177830ENST00000528426E9PQZ0
ENSG00000177830ENST00000528521H0YEA3
ENSG00000177830ENST00000528581Q9BWS9
ENSG00000177830ENST00000529539H0YC89
ENSG00000177830ENST00000530939E9PI70
ENSG00000177830ENST00000531859E9PPA0
ENSG00000177830ENST00000532909H0YDL6
ENSG00000177830ENST00000533056E9PRL3
ENSG00000177830ENST00000533059E9PIP0
ENSG00000177830ENST00000534207H0YCC4
ENSG00000177830ENST00000534254E9PPH0

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359324962022Chitinase domain containing 1 increase is associated with low survival rate and M0 macrophages infiltrates in colorectal cancer patients.3
359324962022Chitinase domain containing 1 increase is associated with low survival rate and M0 macrophages infiltrates in colorectal cancer patients.3
334663162021CHID1 Is a Novel Prognostic Marker of Non-Small Cell Lung Cancer.4
339244682021Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.12
334663162021CHID1 Is a Novel Prognostic Marker of Non-Small Cell Lung Cancer.4
339244682021Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.12
311068672019CHID1 positively regulates RLR antiviral signaling by targeting the RIG-I/VISA signalosome.1
311068672019CHID1 positively regulates RLR antiviral signaling by targeting the RIG-I/VISA signalosome.1
267331602016Role of chitinase-like proteins in cancer.55
267331602016Role of chitinase-like proteins in cancer.55
244703462014Human secreted stabilin-1-interacting chitinase-like protein aggravates the inflammation associated with rheumatoid arthritis and is a potential macrophage inflammatory regulator in rodents.7
244703462014Human secreted stabilin-1-interacting chitinase-like protein aggravates the inflammation associated with rheumatoid arthritis and is a potential macrophage inflammatory regulator in rodents.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
207244792010Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.21
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

CHID1 (chitinase domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54216/teaching-explorer/img/gene-fusions/?id=54216