CLIP2 (CAP-Gly domain containing linker protein 2)

2014-08-01  

Identity

HGNC
CLIP2
LOCATION
7q11.23
LOCUSID
7461
ALIAS
CLIP,CLIP-115,CYLN2,WBSCR3,WBSCR4,WSCR3,WSCR4
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 7461
MIM: 603432
HGNC: 2586
Ensembl: ENSG00000106665

Variants:

dbSNP: 7461
ClinVar: 7461
TCGA: ENSG00000106665
COSMIC: CLIP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106665ENST00000223398Q9UDT6
ENSG00000106665ENST00000361545Q9UDT6
ENSG00000106665ENST00000487447H7C5H8
ENSG00000106665ENST00000493166H7C4L6

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
386500402024Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.0
386500402024Clinical, pathologic, and genomic characteristics of two pediatric glioneuronal tumors with a CLIP2::MET fusion.0
327345982021Whole exome sequencing identifies three novel gene mutations in patients with the triad of diabetic ketoacidosis, hypertriglyceridemia, and acute pancreatitis.6
327345982021Whole exome sequencing identifies three novel gene mutations in patients with the triad of diabetic ketoacidosis, hypertriglyceridemia, and acute pancreatitis.6
308960182019CILP-2 is a novel secreted protein and associated with insulin resistance.13
308960182019CILP-2 is a novel secreted protein and associated with insulin resistance.13
277293732016Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment.12
277293732016Integration of a radiation biomarker into modeling of thyroid carcinogenesis and post-Chernobyl risk assessment.12
252845832015CLIP2 as radiation biomarker in papillary thyroid carcinoma.22
259572512015Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.13
252845832015CLIP2 as radiation biomarker in papillary thyroid carcinoma.22
259572512015Dose-dependent expression of CLIP2 in post-Chernobyl papillary thyroid carcinomas.13
226087122012The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.16
226087122012The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.16
216063602011Gain of chromosome band 7q11 in papillary thyroid carcinomas of young patients is associated with exposure to low-dose irradiation.32

Citation

Dessen P

CLIP2 (CAP-Gly domain containing linker protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54218