CMKLR1 (chemerin chemokine-like receptor 1)

2014-08-01  

Identity

HGNC
CMKLR1
LOCATION
12q23.3
LOCUSID
1240
ALIAS
CHEMERINR,ChemR23,DEZ,RVER1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 1240
MIM: 602351
HGNC: 2121
Ensembl: ENSG00000174600

Variants:

dbSNP: 1240
ClinVar: 1240
TCGA: ENSG00000174600
COSMIC: CMKLR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174600ENST00000312143Q99788
ENSG00000174600ENST00000412676Q99788
ENSG00000174600ENST00000549466F8VSC8
ENSG00000174600ENST00000550402Q99788
ENSG00000174600ENST00000550573F8VYN7
ENSG00000174600ENST00000552995Q99788

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
361567682023Up-regulation of CMKLR1 in endometriosis and its relationship with inflammatory responses.0
368816262023Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.2
371539972023[Chemerin mediated neutrophil infiltration in oral squamous cell carcinoma and predicted poor prognosis].0
371867792023Stable Binding of Full-Length Chemerin Is Driven by Negative Charges in the CMKLR1 N Terminus.0
375390562023ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression.1
361567682023Up-regulation of CMKLR1 in endometriosis and its relationship with inflammatory responses.0
368816262023Cryo-EM structure of the human chemerin receptor 1-Gi protein complex bound to the C-terminal nonapeptide of chemerin.2
371539972023[Chemerin mediated neutrophil infiltration in oral squamous cell carcinoma and predicted poor prognosis].0
371867792023Stable Binding of Full-Length Chemerin Is Driven by Negative Charges in the CMKLR1 N Terminus.0
375390562023ChemR23 activation reprograms macrophages toward a less inflammatory phenotype and dampens carcinoma progression.1
335080122021CCR2/CCL2 and CMKLR1/RvE1 chemokines system levels are associated with insulin resistance in rheumatoid arthritis.1
338495192021Serum resolvin E1 levels and its relationship with thyroid autoimmunity in Hashimoto's thyroiditis: a preliminary study.2
339800472021Expression of Resistin, Chemerin, and Chemerin's Receptor in the Unstable Carotid Atherosclerotic Plaque.6
341694222021GDF-15 Level Correlates with CMKLR1 and VEGF-A in Tumor-free Margin in Colorectal Cancer.8
343393122021SPM Receptor Expression and Localization in Irradiated Salivary Glands.1

Citation

Dessen P

CMKLR1 (chemerin chemokine-like receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54222