CORO7 (coronin 7)

2014-08-01  

Identity

HGNC
CORO7
LOCATION
16p13.3
LOCUSID
79585
ALIAS
0610011B16Rik,CRN7,POD1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 79585
MIM: 611668
HGNC: 26161
Ensembl: ENSG00000262246

Variants:

dbSNP: 79585
ClinVar: 79585
TCGA: ENSG00000262246
COSMIC: CORO7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000262246ENST00000251166P57737
ENSG00000262246ENST00000537233P57737
ENSG00000262246ENST00000570645I3L423
ENSG00000262246ENST00000570779I3L442
ENSG00000262246ENST00000570928I3L359
ENSG00000262246ENST00000571052I3L1T5
ENSG00000262246ENST00000571059I3L2Y6
ENSG00000262246ENST00000571227I3L0Z7
ENSG00000262246ENST00000571756I3L1G9
ENSG00000262246ENST00000572044I3L0X8
ENSG00000262246ENST00000572153I3L482
ENSG00000262246ENST00000572549I3L212
ENSG00000262246ENST00000572898I3L1M1
ENSG00000262246ENST00000573165I3L258
ENSG00000262246ENST00000574025P57737
ENSG00000262246ENST00000574311E7EP81
ENSG00000262246ENST00000575038I3NI06
ENSG00000262246ENST00000575850I3L426
ENSG00000262246ENST00000576051I3L2S7
ENSG00000262246ENST00000576437I3L1Z1
ENSG00000262246ENST00000576637I3L351

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA447197Attention Deficit Disorder with HyperactivityDiseaseClinicalAnnotation, VariantAnnotationassociatedPD29382897
PA450464methylphenidateChemicalClinicalAnnotation, VariantAnnotationassociatedPD29382897

References

Pubmed IDYearTitleCitations
258875382015Implication of coronin 7 in body weight regulation in humans, mice and flies.7
258875382015Implication of coronin 7 in body weight regulation in humans, mice and flies.7
247685392014K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking.79
247685392014K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking.79
211307662011Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.0
211307662011Coronin7 forms a novel E3 ubiquitin ligase complex to promote the degradation of the anti-proliferative protein Tob.0
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
185810492008Molecular mechanism underlying the association of Coronin-7 with Golgi membranes.10
185810492008Molecular mechanism underlying the association of Coronin-7 with Golgi membranes.10
169057712006Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.15
169057712006Crn7 interacts with AP-1 and is required for the maintenance of Golgi morphology and protein export from the Golgi.15
153279922004Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.29
153279922004Coronin 7, the mammalian POD-1 homologue, localizes to the Golgi apparatus.29

Citation

Dessen P

CORO7 (coronin 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54230/js/lib/deep-insight-explorer/favicon/apple-touch-icon.png