ADGRD1 (adhesion G protein-coupled receptor D1)

2014-08-01 Affiliation

Identity

HGNC

ADGRD1

LOCATION

12q24.33

LOCUSID

283383

ALIAS

GPR133,PGR25

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 283383
MIM: 613639
HGNC: 19893
Ensembl: ENSG00000111452

Variants:

dbSNP: 283383
ClinVar: 283383
TCGA: ENSG00000111452
COSMIC: ADGRD1

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000111452	ENST00000261654	Q6QNK2
ENSG00000111452	ENST00000335486	H0Y2U9
ENSG00000111452	ENST00000446583	A0A087WYZ5
ENSG00000111452	ENST00000535015	Q6QNK2
ENSG00000111452	ENST00000542091	F5H7I3
ENSG00000111452	ENST00000543617	Q6QNK2

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
38564758	2024	Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage.	0
38564758	2024	Upregulation of GPR133 expression impaired the phagocytosis of macrophages in recurrent spontaneous miscarriage.	0
34185971	2022	N(6) -methyladenosine (m(6) A) RNA modification of G protein-coupled receptor 133 increases proliferation of lung adenocarcinoma.	5
36457341	2022	ADGRD1 as a Potential Prognostic and Immunological Biomarker in Non-Small-Cell Lung Cancer.	1
34185971	2022	N(6) -methyladenosine (m(6) A) RNA modification of G protein-coupled receptor 133 increases proliferation of lung adenocarcinoma.	5
36457341	2022	ADGRD1 as a Potential Prognostic and Immunological Biomarker in Non-Small-Cell Lung Cancer.	1
27516204	2016	Functional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133).	9
27516204	2016	Functional relevance of naturally occurring mutations in adhesion G protein-coupled receptor ADGRD1 (GPR133).	9
22025619	2011	Cell adhesion receptor GPR133 couples to Gs protein.	51
22025619	2011	Cell adhesion receptor GPR133 couples to Gs protein.	51
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
19729412	2009	Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs.	31
20031603	2009	A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.	43
20031603	2009	A genome-wide association scan of RR and QT interval duration in 3 European genetically isolated populations: the EUROSPAN project.	43

Citation

Dessen P

ADGRD1 (adhesion G protein-coupled receptor D1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54343/js/js/lib/cancer-prone-explorer/