HAO2 (hydroxyacid oxidase 2)

2014-08-01 Affiliation

Identity

HGNC

HAO2

LOCATION

1p12

LOCUSID

51179

ALIAS

GIG16,HAOX2

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 51179
MIM: 605176
HGNC: 4810
Ensembl: ENSG00000116882

Variants:

dbSNP: 51179
ClinVar: 51179
TCGA: ENSG00000116882
COSMIC: HAO2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000116882	ENST00000325945	Q9NYQ3
ENSG00000116882	ENST00000361035	Q9NYQ3
ENSG00000116882	ENST00000457318	Q5QP02
ENSG00000116882	ENST00000622548	Q9NYQ3

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Glyoxylate and dicarboxylate metabolism	KEGG	ko00630
Glyoxylate and dicarboxylate metabolism	KEGG	hsa00630
Peroxisome	KEGG	ko04146
Peroxisome	KEGG	hsa04146
Metabolic pathways	KEGG	hsa01100
Carbon metabolism	KEGG	hsa01200
Carbon metabolism	KEGG	ko01200
Metabolism	REACTOME	R-HSA-1430728
Metabolism of lipids and lipoproteins	REACTOME	R-HSA-556833
Peroxisomal lipid metabolism	REACTOME	R-HSA-390918

References

Pubmed ID	Year	Title	Citations
35528616	2022	Hydroxyacid Oxidase 2 (HAO2) Inhibits the Tumorigenicity of Hepatocellular Carcinoma and Is Negatively Regulated by miR-615-5p.	5
35528616	2022	Hydroxyacid Oxidase 2 (HAO2) Inhibits the Tumorigenicity of Hepatocellular Carcinoma and Is Negatively Regulated by miR-615-5p.	5
31971830	2020	miR-1293 Suppresses Tumor Malignancy by Targeting Hydrocyanic Oxidase 2: Therapeutic Potential of a miR-1293/Hydrocyanic Oxidase 2 Axis in Renal Cell Carcinoma.	5
31971830	2020	miR-1293 Suppresses Tumor Malignancy by Targeting Hydrocyanic Oxidase 2: Therapeutic Potential of a miR-1293/Hydrocyanic Oxidase 2 Axis in Renal Cell Carcinoma.	5
31127626	2019	HAO2 inhibits malignancy of clear cell renal cell carcinoma by promoting lipid catabolic process.	20
31127626	2019	HAO2 inhibits malignancy of clear cell renal cell carcinoma by promoting lipid catabolic process.	20
26658681	2016	The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival.	23
26658681	2016	The metabolic gene HAO2 is downregulated in hepatocellular carcinoma and predicts metastasis and poor survival.	23
19692168	2010	Genetic susceptibility to distinct bladder cancer subphenotypes.	30
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
19692168	2010	Genetic susceptibility to distinct bladder cancer subphenotypes.	30
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20

Citation

Dessen P

HAO2 (hydroxyacid oxidase 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54351