ISX (intestine specific homeobox)

2014-08-01  

Identity

HGNC
ISX
LOCATION
22q12.3
LOCUSID
91464
ALIAS
Pix-1,RAXLX
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 91464
MIM: 612019
HGNC: 28084
Ensembl: ENSG00000175329

Variants:

dbSNP: 91464
ClinVar: 91464
TCGA: ENSG00000175329
COSMIC: ISX

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000175329ENST00000308700Q2M1V0
ENSG00000175329ENST00000404699Q2M1V0

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
373493652023Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case-control study in a Korean population.0
373493652023Interaction between retinol intake and ISX rs5755368 polymorphism in colorectal cancer risk: a case-control study in a Korean population.0
341733482021Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity.5
342653982021Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance.5
341733482021Impact of bromodomain-containing protein 4 (BRD4) and intestine-specific homeobox (ISX) expression on the prognosis of patients with hepatocellular carcinoma' for better clarity.5
342653982021Phosphorylation of intestine-specific homeobox by ERK1 modulates oncogenic activity and sorafenib resistance.5
283986272017Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression.9
286259792017Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression.22
283986272017Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression.9
286259792017Intestine-Specific Homeobox Gene ISX Integrates IL6 Signaling, Tryptophan Catabolism, and Immune Suppression.22
268728902016Intestine-specific homeobox (ISX) induces intestinal metaplasia and cell proliferation to contribute to gastric carcinogenesis.11
271755852016Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC.10
268728902016Intestine-specific homeobox (ISX) induces intestinal metaplasia and cell proliferation to contribute to gastric carcinogenesis.11
271755852016Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC.10
232213822013Proinflammatory homeobox gene, ISX, regulates tumor growth and survival in hepatocellular carcinoma.17

Citation

Dessen P

ISX (intestine specific homeobox)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54387