LSM14A (LSM14A mRNA processing body assembly factor)

2014-08-01 Affiliation

Identity

HGNC

LSM14A

LOCATION

19q13.11

LOCUSID

26065

ALIAS

C19orf13,FAM61A,RAP55,RAP55A

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 26065
MIM: 610677
HGNC: 24489
Ensembl: ENSG00000257103

Variants:

dbSNP: 26065
ClinVar: 26065
TCGA: ENSG00000257103
COSMIC: LSM14A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000257103	ENST00000433627	Q8ND56
ENSG00000257103	ENST00000540746	Q8ND56
ENSG00000257103	ENST00000544216	Q8ND56
ENSG00000257103	ENST00000585887	A0A096LP11
ENSG00000257103	ENST00000586157	K7EMZ9
ENSG00000257103	ENST00000589878	I3L4Q1

Expression (GTEx)

100

150

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
34244294	2021	Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.	7
34244294	2021	Nonstructural Protein NSs Hampers Cellular Antiviral Response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection.	7
28666710	2017	Homozygous alpha-synuclein p.A53V in familial Parkinson's disease.	45
28666710	2017	Homozygous alpha-synuclein p.A53V in familial Parkinson's disease.	45
26940028	2016	Excessive Iron and α-Synuclein Oligomer in Brain are Relevant to Pure Apathy in Parkinson Disease.	10
26940028	2016	Excessive Iron and α-Synuclein Oligomer in Brain are Relevant to Pure Apathy in Parkinson Disease.	10
26339800	2015	Localization and role of RAP55/LSM14 in HeLa cells: a new finding on the mitotic spindle assembly.	6
26339800	2015	Localization and role of RAP55/LSM14 in HeLa cells: a new finding on the mitotic spindle assembly.	6
22614839	2012	PRMT1 is required for RAP55 to localize to processing bodies.	29
22745163	2012	LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.	83
22973032	2012	The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infection.	38
22614839	2012	PRMT1 is required for RAP55 to localize to processing bodies.	29
22745163	2012	LSm14A is a processing body-associated sensor of viral nucleic acids that initiates cellular antiviral response in the early phase of viral infection.	83
22973032	2012	The NS1 protein of influenza A virus interacts with cellular processing bodies and stress granules through RNA-associated protein 55 (RAP55) during virus infection.	38
18723115	2009	RAP55: insights into an evolutionarily conserved protein family.	23

Citation

Dessen P

LSM14A (LSM14A mRNA processing body assembly factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54435/favicon/css/tumors-explorer/