MRPS18A (mitochondrial ribosomal protein S18A)

2014-08-01 Affiliation

Identity

HGNC

MRPS18A

LOCATION

6p21.1

LOCUSID

55168

ALIAS

HumanS18b,MRP-S18-3,MRP-S18-a,MRPS18-3,S18bmt,S18mt-a

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 55168
MIM: 611981
HGNC: 14515
Ensembl: ENSG00000096080

Variants:

dbSNP: 55168
ClinVar: 55168
TCGA: ENSG00000096080
COSMIC: MRPS18A

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000096080	ENST00000372133	Q9NVS2
ENSG00000096080	ENST00000427312	Q5QPA5

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Ribosome	KEGG	ko03010
Ribosome	KEGG	hsa03010
Organelle biogenesis and maintenance	REACTOME	R-HSA-1852241
Mitochondrial translation	REACTOME	R-HSA-5368287
Mitochondrial translation initiation	REACTOME	R-HSA-5368286
Mitochondrial translation elongation	REACTOME	R-HSA-5389840
Mitochondrial translation termination	REACTOME	R-HSA-5419276

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
32391716	2021	Long Noncoding RNA TRIM52-AS1 Sponges miR-514a-5p to Facilitate Hepatocellular Carcinoma Progression Through Increasing MRPS18A.	12
34591434	2021	Expression pattern of MRPS18 family genes in gliomas.	0
32391716	2021	Long Noncoding RNA TRIM52-AS1 Sponges miR-514a-5p to Facilitate Hepatocellular Carcinoma Progression Through Increasing MRPS18A.	12
34591434	2021	Expression pattern of MRPS18 family genes in gliomas.	0
28056857	2017	Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections.	7
28056857	2017	Upregulation of Mrps18a in breast cancer identified by selecting phage antibody libraries on breast tissue sections.	7
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
20628086	2010	Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.	15
20877624	2010	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	20
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105
19913121	2009	Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.	105

Citation

Dessen P

MRPS18A (mitochondrial ribosomal protein S18A)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54471