MTF2 (metal response element binding transcription factor 2)

2014-08-01  

Identity

HGNC
MTF2
LOCATION
1p22.1
LOCUSID
22823
ALIAS
M96,PCL2,TDRD19A,dJ976O13.2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22823
MIM: 609882
HGNC: 29535
Ensembl: ENSG00000143033

Variants:

dbSNP: 22823
ClinVar: 22823
TCGA: ENSG00000143033
COSMIC: MTF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143033ENST00000370298Q9Y483
ENSG00000143033ENST00000370303Q9Y483
ENSG00000143033ENST00000540243Q9Y483
ENSG00000143033ENST00000540243B4DZG1
ENSG00000143033ENST00000545708Q9Y483
ENSG00000143033ENST00000545708B4DZG1

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Epigenetic regulation of gene expressionREACTOMER-HSA-212165
PRC2 methylates histones and DNAREACTOMER-HSA-212300

References

Pubmed IDYearTitleCitations
370279522023Comprehensive Pan-Cancer Analysis of MTF2 Effects on Human Tumors.1
378952282023Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2.2
370279522023Comprehensive Pan-Cancer Analysis of MTF2 Effects on Human Tumors.1
378952282023Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2.2
321551172020PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells.14
321551172020PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells.14
301157032018Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.26
301157032018Targeting the MTF2-MDM2 Axis Sensitizes Refractory Acute Myeloid Leukemia to Chemotherapy.26
259235372015An aromatic cage is required but not sufficient for binding of Tudor domains of the Polycomblike protein family to H3K36me3.13
259235372015An aromatic cage is required but not sufficient for binding of Tudor domains of the Polycomblike protein family to H3K36me3.13

Citation

Dessen P

MTF2 (metal response element binding transcription factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54476/gene-explorer/case-report-explorer/