RALY (RALY heterogeneous nuclear ribonucleoprotein)

2014-08-01  

Identity

HGNC
RALY
LOCATION
20q11.22
LOCUSID
22913
ALIAS
HNRPCL2,P542
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 22913
MIM: 614663
HGNC: 15921
Ensembl: ENSG00000125970

Variants:

dbSNP: 22913
ClinVar: 22913
TCGA: ENSG00000125970
COSMIC: RALY

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125970ENST00000246194Q9UKM9
ENSG00000125970ENST00000333552Q5QPM0
ENSG00000125970ENST00000375114Q9UKM9
ENSG00000125970ENST00000413297Q5QPM2
ENSG00000125970ENST00000442805Q5QPL9
ENSG00000125970ENST00000448364Q5QPM1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
369523482023The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis.1
379063412023SUMOylation of RALY promotes vasculogenic mimicry in glioma cells via the FOXD1/DKK1 pathway.2
369523482023The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis.1
379063412023SUMOylation of RALY promotes vasculogenic mimicry in glioma cells via the FOXD1/DKK1 pathway.2
354909182022RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma.7
359412922022RALY regulate the proliferation and expression of immune/inflammatory response genes via alternative splicing of FOS.5
354909182022RNA binding protein RALY activates the cholesterol synthesis pathway through an MTA1 splicing switch in hepatocellular carcinoma.7
359412922022RALY regulate the proliferation and expression of immune/inflammatory response genes via alternative splicing of FOS.5
332190482021RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.53
337507962021RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2.37
332190482021RNA-binding protein RALY reprogrammes mitochondrial metabolism via mediating miRNA processing in colorectal cancer.53
337507962021RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2.37
320144442020RALY may cause an aggressive biological behavior and a dismal prognosis in non-small-cell lung cancer.11
320144442020RALY may cause an aggressive biological behavior and a dismal prognosis in non-small-cell lung cancer.11
303548392018The hnRNP RALY regulates PRMT1 expression and interacts with the ALS-linked protein FUS: implication for reciprocal cellular localization.7

Citation

Dessen P

RALY (RALY heterogeneous nuclear ribonucleoprotein)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54572