ZFAT (zinc finger and AT-hook domain containing)

2014-08-01  

Identity

HGNC
ZFAT
LOCATION
8q24.22
LOCUSID
57623
ALIAS
AITD3,ZFAT1,ZNF406
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 57623
MIM: 610931
HGNC: 19899
Ensembl: ENSG00000066827

Variants:

dbSNP: 57623
ClinVar: 57623
TCGA: ENSG00000066827
COSMIC: ZFAT

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000066827ENST00000377838Q9P243
ENSG00000066827ENST00000429442F8W7M8
ENSG00000066827ENST00000518191E5RJT2
ENSG00000066827ENST00000519827H0YC51
ENSG00000066827ENST00000520214Q9P243
ENSG00000066827ENST00000520356E9PBN4
ENSG00000066827ENST00000520727Q9P243
ENSG00000066827ENST00000521673H0YBJ1
ENSG00000066827ENST00000522257E5RGN2
ENSG00000066827ENST00000523243E5RH37
ENSG00000066827ENST00000523399Q9P243
ENSG00000066827ENST00000523924E5RJL9

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
361625102022Death domain-associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT.1
361625102022Death domain-associated protein DAXX regulates noncoding RNA transcription at the centromere through the transcription regulator ZFAT.1
345472892021CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA.4
345472892021CENP-B promotes the centromeric localization of ZFAT to control transcription of noncoding RNA.4
312705532020Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women.4
329971152020ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B-H4K8ac-BRD4 axis.9
312705532020Identification of pelvic organ prolapse risk susceptibility gene SNP locus in Xinjiang women.4
329971152020ZFAT binds to centromeres to control noncoding RNA transcription through the KAT2B-H4K8ac-BRD4 axis.9
313665512019Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver.1
313665512019Zfat Is Indispensable for the Development of Erythroid Cells in the Fetal Liver.1
286270892017Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease.4
286270892017Analysis of PTPN22, ZFAT and MYO9B polymorphisms in Turner Syndrome and risk of autoimmune disease.4
275728282016ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility.3
275728282016ZFAT gene variant association with multiple sclerosis in the Arabian Gulf population: A genetic basis for gender-associated susceptibility.3
258018602015Solution structures of the DNA-binding domains of immune-related zinc-finger protein ZFAT.10

Citation

Dessen P

ZFAT (zinc finger and AT-hook domain containing)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54797/gene-explorer/tumors-explorer/tumors-explorer/