HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B)

2014-08-01  

Identity

HGNC
HNRNPAB
LOCATION
5q35.3
LOCUSID
3182
ALIAS
ABBP1,HNRPAB
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 3182
MIM: 602688
HGNC: 5034
Ensembl: ENSG00000197451

Variants:

dbSNP: 3182
ClinVar: 3182
TCGA: ENSG00000197451
COSMIC: HNRNPAB

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197451ENST00000355836Q99729
ENSG00000197451ENST00000358344Q99729
ENSG00000197451ENST00000504898Q99729
ENSG00000197451ENST00000506259Q99729
ENSG00000197451ENST00000506339D6RBZ0
ENSG00000197451ENST00000514633D6RD18
ENSG00000197451ENST00000515193D6R9P3

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371659202023Knockdown of hnRNPAB reduces the stem cell properties and enhances the chemosensitivity of human colorectal cancer stem cells.1
382794692023Impact of heterogeneous nuclear ribonucleoprotein A/B subtype overexpression on the expression of cancer stem cell markers CD133 and CD44 and cellular proliferation capacity.0
371659202023Knockdown of hnRNPAB reduces the stem cell properties and enhances the chemosensitivity of human colorectal cancer stem cells.1
382794692023Impact of heterogeneous nuclear ribonucleoprotein A/B subtype overexpression on the expression of cancer stem cell markers CD133 and CD44 and cellular proliferation capacity.0
343964272021MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.5
343964272021MicroRNA‑8063 targets heterogeneous nuclear ribonucleoprotein AB to inhibit the self‑renewal of colorectal cancer stem cells via the Wnt/β‑catenin pathway.5
310900622020HNRNPAB-regulated lncRNA-ELF209 inhibits the malignancy of hepatocellular carcinoma.16
310900622020HNRNPAB-regulated lncRNA-ELF209 inhibits the malignancy of hepatocellular carcinoma.16
287638642017[High expression of hnRNPAB/Kap1 together promote poor prognosis in HCC].1
287638642017[High expression of hnRNPAB/Kap1 together promote poor prognosis in HCC].1
246389792014HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.57
246389792014HNRNPAB induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by transcriptionally activating SNAIL.57
126921352003P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.29
126921352003P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.29

Citation

Dessen P

HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54824/css/css/gene-fusions-explorer/