CFAP45 (cilia and flagella associated protein 45)

2014-08-01  

Identity

HGNC
CFAP45
LOCATION
1q23.2
LOCUSID
25790
ALIAS
CCDC19,NESG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 25790
MIM: 605152
HGNC: 17229
Ensembl: ENSG00000213085

Variants:

dbSNP: 25790
ClinVar: 25790
TCGA: ENSG00000213085
COSMIC: CFAP45

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000213085ENST00000368099Q9UL16
ENSG00000213085ENST00000426543Q9UL16
ENSG00000213085ENST00000476696A0A087X182
ENSG00000213085ENST00000479940A0A087WUV1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
372363562023The cilia and flagella associated protein CFAP52 orchestrated with CFAP45 is required for sperm motility in mice.1
372363562023The cilia and flagella associated protein CFAP52 orchestrated with CFAP45 is required for sperm motility in mice.1
337883462021VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.3
337883462021VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.3
331397252020CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.22
331397252020CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module.22
304423692018Long noncoding RNA MAGI2-AS3 regulates CCDC19 expression by sponging miR-15b-5p and suppresses bladder cancer progression.32
304423692018Long noncoding RNA MAGI2-AS3 regulates CCDC19 expression by sponging miR-15b-5p and suppresses bladder cancer progression.32
249765362014Candidate tumour suppressor CCDC19 regulates miR-184 direct targeting of C-Myc thereby suppressing cell growth in non-small cell lung cancers.29
249765362014Candidate tumour suppressor CCDC19 regulates miR-184 direct targeting of C-Myc thereby suppressing cell growth in non-small cell lung cancers.29
229970982012Proteomic features of potential tumor suppressor NESG1 in nasopharyngeal carcinoma.8
229970982012Proteomic features of potential tumor suppressor NESG1 in nasopharyngeal carcinoma.8
207151682011Decreased expression of updated NESG1 in nasopharyngeal carcinoma: its potential role and preliminarily functional mechanism.28
221404792011Potential tumor suppressor NESG1 as an unfavorable prognosis factor in nasopharyngeal carcinoma.15
207151682011Decreased expression of updated NESG1 in nasopharyngeal carcinoma: its potential role and preliminarily functional mechanism.28

Citation

Dessen P

CFAP45 (cilia and flagella associated protein 45)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54829/css/gene-fusions-explorer/meetings/